Diagnostic and Prognostic Value of cfDNA Concentration and Fragmentation in Prostate Cancer
ABSTRACT Objective To evaluate the value of circulating free DNA (cfDNA) in prostate cancer (PCa) by cfDNA assay and analysis of plasma and urinary cfDNA fragmentation to determine the usefulness of this parameter for risk staging and tumor progression monitoring.
Marta Victoria Lorenzo‐Sánchez +8 more
wiley +1 more source
Molecular insights into salt stress response in perennial ryegrass (<i>Lolium perenne</i> L.): gene expression and growth performance assessment. [PDF]
Yıldırım GH +3 more
europepmc +1 more source
Abstract Anthropogenic climate change affects regional hydrological cycles and poses significant challenges to the sustainable supply of freshwater. The Central China water tower (CCWT) is the key source region feeding the Yangtze and Yellow Rivers, and its runoff is indispensable for the surrounding mega‐city clusters. Here we present a reconstruction
Weipeng Yue +18 more
wiley +1 more source
Miniature bioreactor arrays for modeling functional and structural dysbiosis in inflammatory bowel disease. [PDF]
Newman KL +9 more
europepmc +1 more source
Abstract The Late Cretaceous Oman ophiolite includes a series of volcanic rocks generated during the transition from spreading ridge to protoarc associated with subduction initiation. We analyzed major and trace elements and Sr, Nd, and Pb isotope compositions of lavas and dikes of the protoarc stage, especially boninites. We also analyzed amphibolites
Tsuyoshi Ishikawa +6 more
wiley +1 more source
Effects of hydroxy methionine analog iron chelate on growth performance, blood parameters, and iron metabolism in weaned piglets. [PDF]
Fu Y +9 more
europepmc +1 more source
EMA/HMA - HMA-EMA joint Big Data Steering Group: publication of the updated 2023-2025 workplan
The HMA-EMA joint Big Data Steering Group updated and published its 2023-2025 workplan. This document introduces each topic and outlines key deliverables. The plan was informed by stakeholder and expert consultation. The document is structured in line with the key recommendations of the Big Data Task Force (see Annex I).
openaire +1 more source
Abstract Understanding how spatially variable mountain‐building processes proceed within large intracontinental orogens provides critical insights into continental tectonics and regional paleoenvironmental evolution. Here, we address this issue in the central South Tian Shan (cSTS), a key transitional segment between the well‐studied eastern and ...
Feng Li +11 more
wiley +1 more source
CHEK2 loss endows chemotherapy resistance to hematopoietic stem cells. [PDF]
Zhou J +6 more
europepmc +1 more source
EMA/HMA – List of metadata for the HMA-EMA Catalogues of realworld data sources and studies
The EMA recently published a List of metadata for the HMA-EMA Catalogues of realworld data sources and studies. In line with the Big Data Steering Group workplan and the European medicines agencies network Strategy to 2025 action on data discoverability, and through consultation with its stakeholders, EMA produced a list of metadata for describing real-
openaire +2 more sources

