Results 181 to 190 of about 54,581 (294)
EMA/HMA - HMA-EMA joint Big Data Steering Group: publication of the updated 2023-2025 workplan
The HMA-EMA joint Big Data Steering Group updated and published its 2023-2025 workplan. This document introduces each topic and outlines key deliverables. The plan was informed by stakeholder and expert consultation. The document is structured in line with the key recommendations of the Big Data Task Force (see Annex I).
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Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.This article reveals how calcium content, mineral nanostructure, and lacuno‐canalicular network (LCN) organization interact to shape bone heterogeneity in mouse tibiae. Advanced multimodal imaging uncovers that mechanical loading promotes mature mineral structures even in low‐calcium regions, highlighting LCN‐driven mineralization and offering new ...
Victoria Schemenz +10 more
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EMA/HMA – List of metadata for the HMA-EMA Catalogues of realworld data sources and studies
The EMA recently published a List of metadata for the HMA-EMA Catalogues of realworld data sources and studies. In line with the Big Data Steering Group workplan and the European medicines agencies network Strategy to 2025 action on data discoverability, and through consultation with its stakeholders, EMA produced a list of metadata for describing real-
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Superficial Femoral Artery Spontaneous Pseudoaneurysm Revealing Pleomorphic Vascular Wall Sarcoma
Clinical Case Reports, Volume 14, Issue 5, May 2026.Spontaneous femoral artery pseudoaneursym with contrast media extrvasation. ABSTRACT Vascular malignancy may rarely present as soft tissue swelling related to a spontaneous pseudoaneurysm. Our case report highlights the importance of prompt clinical examination, imaging, and surgical exploration for diagnosing vascular sarcoma presenting as a ...
Kamal Majed +3 more
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Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1288-1297, May 2026.The European Medicines Regulatory Network plays a critical role in safeguarding public health through the assessment and supervision of human medicines. However, rapid scientific and technological advancements have exposed capability deficits across the network, threatening timely and effective regulatory decision‐making.
Naomi Beard +4 more
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Influence of different therapy strategies in patients with myelodysplastic neoplasms (MDS) on overall survival with regard to different decades: data from the German MDS registry. [PDF]
Ann HematolWelsch J +13 more
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Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.• XPO1 hyperactivation promotes leukaemogenesis by altering nucleocytoplasmic transport and transcriptional control in acute myeloid leukaemia (AML). • Selinexor and eltanexor show preferential activity in NPM1‐mutated, DEK::NUP214‐positive and SF3B1‐mutated myeloid neoplasms.
Yifan Liu +4 more
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Environmental DNA, Volume 8, Issue 3, May–June 2026.Filters and freshwater sponge tissue recover a comparable number of taxa through eDNA metabarcoding. Filters detect more taxa, followed by sponge tissue when host‐blocking primers are used. Each method reveals different community compositions, so combining both approaches is recommended to achieve a more realistic representation of the metazoan ...
Andrea Corral‐Lou +8 more
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Mechanistic overview and suggested strategies to overcome BCL-2 inhibitor resistance in <i>TP53-</i>mutated acute myeloid leukemia. [PDF]
Front Cell Dev BiolIqbal U, Shallis RM.
europepmc +1 more source