Results 61 to 70 of about 2,525,333 (167)
Animals, 2021 The choice of optimal reference gene is challenging owing to the varied expression of reference genes in different organs, development stages, and experimental treatments. Brandt’s vole (Lasiopodomys brandtii) is an ideal animal to explore the regulatory
Lin Tian +3 more
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Scientific Reports, 2020 Due to the limitations in the range of antibodies recognising avian viruses, quantitative real-time PCR (RT-qPCR) is still the most widely used method to evaluate the expression of immunologically related genes in avian viruses.
Sook Yee Boo +5 more
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HMBS: a statechart-based model for hyperdocuments formal specification
, 2014 Um novo modelo para a especificação de hiperdocumentos denominado HMBS - Hyperdocument Model Based on Statecharts - é proposto. O HMBS adota como modelo formal subjacente a técnica Statecharts, cuja estrutura e semântica operacional são utilizadas para ...
Turine, Marcelo Augusto Santos
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Journal of Applied HematologyMutations in the hydroxymethylbilane synthase (HMBS) gene can lead to a deficiency of the HMBS enzyme, allowing porphyrins to accumulate to toxic levels in the liver and other organs, leading to acute intermittent porphyria (AIP).
Abeer Zakariyah* +9 more
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Identification of optimal endogenous reference RNAs for RT-qPCR normalization in hindgut of rat models with anorectal malformations [PDF]
PeerJ, 2019 Background Quantitative real-time polymerase chain reaction (RT-qPCR) is a sensitive method for quantifying mRNA abundance. With relative expression analysis, however, reliable data output is dependent on stably expressed reference genes across the ...
Caiyun Long +5 more
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Influence of heat stress, sex and genetic groups on reference genes stability in muscle tissue of chicken. [PDF]
PLoS ONE, 2017 Quantitative RT-PCR is an important technique for assessing gene expression. However, a proper normalization of reference genes prior to expression analyses of target genes is necessary.
Haniel Cedraz de Oliveira +5 more
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Title: An Analysis of HMBS Variants Associated with Acute Intermittent Porphyria [PDF]
AIP, also known as acute intermittent porphyria is a disease commonly characterized by the deficiency of hydroxymethylbilane synthase (HMBS). It presents itself with abdominal pain nausea, vomiting, peripheral neuropathy, and seizures.
Kahari, Jason, Vanterpool, Elaine
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A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues. [PDF]
PLoS ONE, 2010 Because many species-specific phenotypic differences are assumed to be caused by differential regulation of gene expression, many recent investigations have focused on measuring transcript abundance. Despite the availability of high-throughput platforms,
Olivier Fedrigo +5 more
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Hmbs Mutations in Chinese Patients with Acute Intermittent Porphyria
, 2011 Acute intermittent porphyria (AIP), an autosomal dominant disorder, is caused by partial deficiency of hydroxymethylbilane synthase (HMBS) affecting heme biosynthesis.
YANG, CHIH-CHAO;KUO, HUNG-CHOU;YOU, HUEY-LING;HUANG, CHIN-CHANG;LEE, MING-JEN +1 more
core
Assessing predictions on fitness effects of missense variants in HMBS in CAGI6 [PDF]
This paper presents an evaluation of predictions submitted for the "HMBS" challenge, a component of the sixth round of the Critical Assessment of Genome Interpretation held in 2021.
Jagota M. +30 more
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