Results 171 to 180 of about 57,220 (227)

Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase. [PDF]

Proc Natl Acad Sci U S A
Faulkner RA, Yang Y, Tsien J, Qin T, DeBose-Boyd RA.   +4 more
europepmc   +1 more source

Effects of Cynara scolymus L. Bract Extract on Lipid Metabolism Disorders Through Modulation of HMG-CoA Reductase, Apo A-1, PCSK-9, p-AMPK, SREBP-2, and CYP2E1 Expression. [PDF]

Metabolites
Mokhtari I, Shahat AA, Noman OM, Milenkovic D, Amrani S, Harnafi H.   +5 more
europepmc   +1 more source

Regulation of rat liver microsomal cholesterol 7α-hydroxylase: Presence of a cytosolic activator [PDF]

, 1981
Burnett, William, Hardie, Ian R., Kwok, Chea T.   +2 more
core  

Antioxidant and Inhibitory Activities of Filipendula glaberrima Leaf Constituents against HMG-CoA Reductase and Macrophage Foam Cell Formation. [PDF]

Molecules
Cho YB, Lee H, Jeon HJ, Lee JY, Kim HJ.
europepmc   +1 more source

In vitro and in silico studies of the potential cytotoxic, antioxidant, and HMG CoA reductase inhibitory effects of chitin from Indonesia mangrove crab (Scylla serrata) shells. [PDF]

Saudi J Biol Sci
Fajriaty I, Fidrianny I, Kurniati NF, Fauzi NM, Mustafa SH, Adnyana IK.   +5 more
europepmc   +1 more source

In Silico Analysis of Selected Mikania Constituents As Human HMG-CoA Reductase, Human Inducible Nitric Oxide Synthase, and Human Squalene Synthase Inhibitory Agents. [PDF]

Cureus
Vijayakumar STV, Narayanaswamy R, Prabhakaran VS.   +2 more
europepmc   +1 more source

Drug Target Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Atrial Fibrillation.

Cardiology
Li F, Mei Y, Wu Q, Wu X.
europepmc   +1 more source

Graft protective effects and donor-specific antibody suppression by CD4⁺CD25⁺Foxp3⁺ regulatory T cell induced by HMG-CoA reductase inhibitor rosuvastatin in a murine heart transplant model. [PDF]

J Cardiothorac Surg
Iguchi K, Yamamoto Y, Uchiyama M, Masaoka H, Nakamura M, Shizuka H, Imazuru T, Shimokawa T.   +7 more
europepmc   +1 more source

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HMG-CoA reductase inhibitors

Natural Product Reports, 1993
Since in humans the greater part of the cholesterol in the body is synthesized de novo in the liver and intestine, the search for drugs to inhibit cholesterol biosynthesis has long been pursued as a means to lower the level of plasma cholesterol and so help to prevent and treat atherosclerosis.
A, Endo, K, Hasumi
  +5 more sources

HMG CoA reductase inhibitors

Current Opinion in Lipidology, 1994
Beta-hydroxy-beta-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors (HMG CoA RIs) are now being prescribed in many different countries, and the number of patients treated with these compounds is estimated to be over 1.5 million. The spectrum of indications for these drugs is enlarging.
openaire   +3 more sources