Results 91 to 100 of about 87,902 (279)

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

A Study of the Quasi-elastic (e,e'p) Reaction on $^{12}$C, $^{56}$Fe and $^{97}$Au

, 2003
We report the results from a systematic study of the quasi-elastic (e,e'p) reaction on $^{12}$C, $^{56}$Fe and $^{197}$Au performed at Jefferson Lab. We have measured nuclear transparency and extracted spectral functions (corrected for radiation) over a ...
A. Ahmidouch, A. Klein, A. Lung, A. M. Nathan, A. Mateos, B. Terburg, B. Zeidman, B. Zihlmann, C. Armstrong, C. Bochna, C. Cothran, C. Jackson, C. Jones, C. Keppel, C. Salgado, C. Williamson, C. Yan, D. Abbott, D. Beatty, D. Day, D. DeSchepper, D. Dutta, D. F. Geesaman, D. J. Mack, D. Koltenuk, D. Meekins, D. Potterveld, D. van Westrum, E. Beise, E. Belz, E. E. W. Bruins, E. Kinney, F. Duncan, F. G. Perey, G. Niculescu, H. Breuer, H. E. Jackson, H. Gao, H. Mkrtchyan, H. T. Fortune, I. Niculescu, J. Arrington, J. Arrington, J. Cha, J. D. Walecka, J. Dunne, J. J. Kelly, J. J. Kelly, J. Martin, J. Mitchell, J. O. Hansen, J. P. Schiffer, J. Reinhold, J. W. Price, J. Yu, J.-C. Yang, J.-E. Ducret, K. A. Assamagan, K. Bailey, K. Beard, K. McFarlane, L. Kramer, L. Tang, M. A. Miller, M. Gari, M. Khandaker, N. Chant, O. K. Baker, P. E. Bosted, P. Guèye, P. Markowitz, P. Stoler, R. Carlini, R. E. Segel, R. Ent, R. Gilman, R. Hofstadter, R. J. Holt, R. Madey, R. Milner, R. Mohring, R. Suleiman, S. Barrow, S. Beedoe, S. Danagoulian, S. Frullani, S. Kaufman, S. Wood, T. Eden, T. G. O’Neill, T. P. Welch, Ts. A. Amatuoni, V. Frolov, V. Tadevosyan, W. Hinton, W. J. Cummings, W. Kim, W. Lorenzon, W. Zhao   +98 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Dr. Novel and Dr. Sage: Developing Expertise in Leading Small-Group Discussions

MedEdPORTAL, 2014
Introduction As medical schools increasingly move toward student-centered, interactive learning approaches that promote active student engagement and critical thinking skills, there is a clear trend to employ teaching methods that emphasize collaborative,
Laurie Fishman, Lori Newman
doaj   +1 more source

Prime, Perform, Recover [PDF]

, 2017
This thesis examines the formal and conceptual framework of my artistic practice as it culminated in the installation of my thesis exhibition, Prime, Perform, Recover.
Harkin, Patrick
core   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

A Strain Decoupling Packaging Strategy for High‐Fidelity Ultrathin Silicon Shape Sensors for Soft Medical Robotics

Advanced Science, EarlyView.
Reliable soft sensors are essential for precise control in soft medical robots such as endoscopes. We developed ultrathin silicon piezoresistive sensors and their oil‐lubricated slidable packaging, which enables high‐fidelity shape sensing of silicon gauges by mechanically isolating the sensing element within a dual‐layer film.
Hao Liu, Masahito Takakuwa, Michitaka Yamamoto, Yiwen Wang, Tomoyuki Yokota, Takao Someya, Toshihiro Itoh, Seiichi Takamatsu   +7 more
wiley   +1 more source

Chemical Upcycling of Polyphenylene Sulfide at Room Temperature

Advanced Science, EarlyView.
Poly(phenylene sulfide) (PPS) is a semi‐crystalline super engineering plastic with exceptional properties. An iron‐photocatalyzed strategy is reported for chemical upcycling of PPS plastics at room temperature using 1,2‐dichloroethane. The method demonstrates remarkable efficiency across diverse PPS resins and post‐consumer composites, even within ...
Boning Gu, Chengliang Li, Xuefeng Jiang
wiley   +1 more source

Homological mirror symmetry for local Calabi-Yau manifolds via SYZ

, 2016
This is a write-up of the author's talk in the conference "Algebraic Geometry in East Asia 2016" held at the University of Tokyo in January 2016. We give a survey on a series of papers of the author and his collaborators Daniel Pomerleano and Kazushi ...
Chan, Kwokwai
core   +1 more source

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

Advanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source