Results 21 to 30 of about 87,902 (279)

Optimising content clarity for human-machine systems [PDF]

open access: yes, 2007
This paper details issues associated with the production of clearly expressed and comprehensible technical documentation for domestic appliances and human-machine systems, and describes an approach to optimising the clarity of such content. The aim is to
Anagnostou, N.K., Weir, George
core   +2 more sources

Progression of Metastasis through Lymphatic System

open access: yesCells, 2021
Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate.
Hengbo Zhou   +2 more
doaj   +1 more source

A High-Throughput Small Molecule Screen Identifies Ouabain as Synergistic with miR-34a in Killing Lung Cancer Cells

open access: yesiScience, 2020
Summary: MicroRNA-34 (miR-34) is one of the major families of tumor suppressor miRNAs often lost in cancers. Delivery of miR-34a mimics to affected tumors as a therapeutic strategy has been tried in pre-clinical studies and in a phase I clinical trial ...
Rajesha Rupaimoole   +4 more
doaj   +1 more source

Immobilization of heavy metals in sewage sludge by using subcritical water technology [PDF]

open access: yes, 2013
Heavy metals (HMs) immobilization in sewage sludge was investigated by using subcritical water technology (SCWT) in this study. The characteristics of sludge and toxicity of HMs were analyzed after SCWT process.
Ding Dahu   +9 more
core   +1 more source

Improving Access to HLA-Matched Kidney Transplants for African American Patients

open access: yesFrontiers in Immunology, 2022
IntroductionKidney transplants fail more often in Black than in non-Black (White, non-Black Hispanic, and Asian) recipients. We used the estimated physicochemical immunogenicity for polymorphic amino acids of donor/recipient HLAs to select weakly ...
Dulat Bekbolsynov   +8 more
doaj   +1 more source

Targeting Histone Modifications in Breast Cancer: A Precise Weapon on the Way

open access: yesFrontiers in Cell and Developmental Biology, 2021
Histone modifications (HMs) contribute to maintaining genomic stability, transcription, DNA repair, and modulating chromatin in cancer cells. Furthermore, HMs are dynamic and reversible processes that involve interactions between numerous enzymes and ...
Wei Li   +6 more
doaj   +1 more source

Development and in vitro safety evaluation of pramipexole-loaded hollow mesoporous silica (HMS) particles

open access: yesBiotechnology & Biotechnological Equipment, 2019
In this study, spherical hollow mesoporous silica (HMS) particles with average size of 550 nm were loaded with dopamine-receptor agonist pramipexole, as a model drug. High drug loading (55%) was achieved by its incorporation in the reservoir structure of
Borislav Tzankov   +7 more
doaj   +1 more source

Differential DARC/ACKR1 expression distinguishes venular from non-venular endothelial cells in murine tissues

open access: yesBMC Biology, 2017
Background Intravascular leukocyte recruitment in most vertebrate tissues is restricted to postcapillary and collecting venules, whereas capillaries and arterioles usually support little or no leukocyte adhesion.
Aude Thiriot   +11 more
doaj   +1 more source

Diastereoselective metabolism of homomenthyl salicylate (homosalate): Identification of relevant human exposure biomarkers

open access: yesEnvironment International, 2022
Homosalate (HMS) is a salicylate UV filter broadly used in sunscreens and personal care products. The aim of this study was the collection of human toxicokinetic data on HMS as a tool for risk assessment.
Katharina E. Ebert   +6 more
doaj   +1 more source

From favorable atomic configurations to supershell structures: a new interpretation of conductance histograms

open access: yes, 2000
Title: From favorable atomic configurations to supershell structures: a new interpretation of conductance histograms Authors: A. Hasmy (IVIC), E. Medina (IVIC), P.A.
A. Buldum   +50 more
core   +1 more source

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