Results 21 to 30 of about 17,319 (267)

Diastereoselective metabolism of homomenthyl salicylate (homosalate): Identification of relevant human exposure biomarkers

open access: yesEnvironment International, 2022
Homosalate (HMS) is a salicylate UV filter broadly used in sunscreens and personal care products. The aim of this study was the collection of human toxicokinetic data on HMS as a tool for risk assessment.
Katharina E. Ebert   +6 more
doaj   +1 more source

Progression of Metastasis through Lymphatic System

open access: yesCells, 2021
Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate.
Hengbo Zhou   +2 more
doaj   +1 more source

Low Hydrophobic Mismatch Scores Calculated for HLA-A/B/DR/DQ Loci Improve Kidney Allograft Survival

open access: yesFrontiers in Immunology, 2020
We evaluated the impact of human leukocyte antigen (HLA) disparity (immunogenicity; IM) on long-term kidney allograft survival. The IM was quantified based on physicochemical properties of the polymorphic linear donor/recipient HLA amino acids (the ...
Dulat Bekbolsynov   +13 more
doaj   +1 more source

Artificial intelligence in heavy metals detection: Methodological and ethical challenges

open access: yesHygiene and Environmental Health Advances, 2023
Heavy metals (HMs) are metallic substances. They enter biotic and abiotic systems through natural and human activities. These HMs have an impact on the atmosphere, soil, and groundwater, and they also affect all living things, especially humans, when ...
Nidhi Yadav   +11 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Event‐related potentials during sustained attention and memory tasks: Utility as biomarkers for mild cognitive impairment

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction The objective of the study is to validate attention and memory tasks that elicit event‐related potentials (ERPs) for utility as sensitive biomarkers for early dementia.
Shani Waninger   +8 more
doaj   +1 more source

Clinical application of short tandem repeat polymorphism analysis in the differential diagnosis of early hydatidiform mole and hydropic abortion

open access: yesClinical and Experimental Obstetrics & Gynecology, 2020
Objective: To determine the clinical differential diagnosis value of short tandem repeat polymorphism (STR) analysis in early hydatidiform moles (HMs) and non-molar gestations.
J. Wang   +5 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Effects of heavy metals speciations in sediments on their bioaccumulation in wild fish in rivers in Liuzhou—A typical karst catchment in southwest China

open access: yesEcotoxicology and Environmental Safety, 2021
Although fish are widely confirmed to be susceptible to heavy metals (HMs) contamination in sediments, this bioconversion haven’t been detailed. This is especially the case in karst areas, where HMs are less stably retained in the sediments and are more ...
Xiongyi Miao   +5 more
doaj   +1 more source

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo   +3 more
wiley   +1 more source

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