Results 81 to 90 of about 123,814 (303)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
What’s Cool About Hot Stars? Cataclysmic Variables in the Mid-Infrared [PDF]
We review recent results from mid-infrared observations of cataclysmic variables with the Spitzer Space Telescope. In general, these observations have revealed mid-infrared excesses, above the level expected from the stellar and accretion components, in ...
Brinkworth, C. +6 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Spartan Daily, December 3, 1986 [PDF]
Volume 87, Issue 64https://scholarworks.sjsu.edu/spartandaily/7521/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +3 more sources
A Spitzer Space Telescope Study of the Debris Disks around four SDSS White Dwarfs [PDF]
We present Spitzer Space Telescope data of four isolated white dwarfs that were previously known to harbor circumstellar gaseous disks. IRAC photometry shows a significant infrared excess in all of the systems, SDSS0738+1835, SDSS0845+2257, SDSS1043+0855
Abazajian +45 more
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Taming the Invisible Monster: System Parameter Constraints for Epsilon Aurigae from the Far-Ultraviolet to the Mid-Infrared [PDF]
We have assembled new Spitzer Space Telescope Infrared Array Camera observations of the mysterious binary star Epsilon Aurigae, along with archival far-ultraviolet to mid-infrared data, to form an unprecedented spectral energy distribution spanning three
Ake +49 more
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A Survey of Far Ultraviolet Spectroscopic Explorer Observations of Cataclysmic Variables
During its lifetime, the Far Ultraviolet Spectroscopic Explorer (FUSE) was used to observe 99 cataclysmic variables in 211 separate observations. Here, we present a survey of the moderate resolution (R\simeq10,000), far-ultraviolet (905 - 1188 {\deg}A ...
Araujo-Betancor +60 more
core +1 more source

