Results 121 to 130 of about 9,263,948 (394)

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner   +7 more
wiley   +1 more source

Iterative Implicit Methods for Solving Hodgkin-Huxley Type Systems

open access: yes, 2019
We are motivated to approximate solutions of a Hodgkin-Huxley type model with implicit methods. As a representative we chose a psychiatric disease model containing stable as well as chaotic cycling behaviour.
Geiser, Juergen, Ogiermann, Dennis
core  

CD86, the double agent: Significance of CD86 expression in B‐cell malignancies

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Gábor Barna   +4 more
wiley   +1 more source

Socioeconomic background and childhood cancer survival in Germany: A nationwide assessment based on data from the German Childhood Cancer Registry

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Significant advances in childhood cancer survival have transformed outcomes for many children globally. However, emerging evidence suggests that, even in settings with universal healthcare, these gains are not equally distributed. Here, the authors focused on childhood cancer survival in Germany, using data from the German Childhood Cancer ...
Maike Wellbrock   +7 more
wiley   +1 more source

CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma

open access: yesHaematologica, 2018
Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory or relapsed disease ...
Ziduo Li   +21 more
doaj   +1 more source

Impact of salvage treatment on initial relapses in patients with Hodgkin disease, stages I-III [PDF]

open access: bronze, 1978
Portlock Cs   +3 more
openalex   +1 more source

Life Is in the Blood [PDF]

open access: yes, 2019
It takes about 60 seconds for all the blood in your body to complete its journey. It travels from your heart to your extremities and returns, there and back again.
Conrad, Jason, Gillen, Alan L.
core   +1 more source

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