Results 121 to 130 of about 9,263,948 (394)
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source
Mediastinal Form of Lymphadenoma (Hodgkins Disease) with Extreme So-Called Pulmonary Hypertrophic Osteoarthropathy [PDF]
F. Parkes Weber, J. C. G. Ledingham
openalex +1 more source
Iterative Implicit Methods for Solving Hodgkin-Huxley Type Systems
We are motivated to approximate solutions of a Hodgkin-Huxley type model with implicit methods. As a representative we chose a psychiatric disease model containing stable as well as chaotic cycling behaviour.
Geiser, Juergen, Ogiermann, Dennis
core
CD86, the double agent: Significance of CD86 expression in B‐cell malignancies
Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Gábor Barna+4 more
wiley +1 more source
Viral-Related RNA in Hodgkins' Disease and Other Human Lymphomas [PDF]
R. Hehlmann, Donald Küfe, S. Spiegelman
openalex +1 more source
What's New? Significant advances in childhood cancer survival have transformed outcomes for many children globally. However, emerging evidence suggests that, even in settings with universal healthcare, these gains are not equally distributed. Here, the authors focused on childhood cancer survival in Germany, using data from the German Childhood Cancer ...
Maike Wellbrock+7 more
wiley +1 more source
CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma
Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory or relapsed disease ...
Ziduo Li+21 more
doaj +1 more source
Impact of salvage treatment on initial relapses in patients with Hodgkin disease, stages I-III [PDF]
Portlock Cs+3 more
openalex +1 more source
It takes about 60 seconds for all the blood in your body to complete its journey. It travels from your heart to your extremities and returns, there and back again.
Conrad, Jason, Gillen, Alan L.
core +1 more source