Results 51 to 60 of about 1,399 (114)

Genetic Diversity of Highly Pathogenic Avian Influenza Viruses Isolated in Hokkaido, Japan, During Winter 2024–2025

Pathogens
Genetic and antigenic analyses were performed on highly pathogenic avian influenza viruses (HPAIVs) isolated in Hokkaido, northern Japan, during the winter of 2024–2025.
Norikazu Isoda, Lim Yik Hew, Kazuki Nishikawa, Fumihito Takaya, Yo Shimazu, Daiki Kobayashi, Kei Nabeshima, Hisako Honjyo, Mana Esaki, Kosuke Okuya, Kosuke Soda, Hiroshi Ito, Asuka Kumagai, Hayate Nishiura, Takahiro Hiono, Hiroki Takakuwa, Tatsufumi Usui, Makoto Ozawa, Yuko Uchida, Manabu Onuma, Yoshihiro Sakoda   +20 more
doaj   +1 more source

Genetic and Antigenic Characterization and Retrospective Surveillance of Bovine Influenza D Viruses Identified in Hokkaido, Japan from 2018 to 2020

Viruses, 2020
Influenza D virus (IDV), which is a new member of the Orthomyxoviridae family, is potentially involved in bovine respiratory diseases (BRDs). Bovine IDVs (BIDVs) from Japan have been distributed nationwide since 2010 and are genetically distinct from ...
Jun Hayakawa, Tomomi Masuko, Tae Takehana, Tohru Suzuki   +3 more
doaj   +1 more source

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

British Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa, Daiki Tsuji, Masahiro Hatori, Kazuyoshi Kawakami, Masahiko Nakao, Takuya Yano, Yuichiro Arakawa, Keisuke Matsuo, Yasukata Ohashi, Masato Ozaka, Naoki Sasahira, Yasuhiko Sakata, Yuki Kogure, Shinya Tamaki, Atsushi Wada, Yusuke Taki, Wataru Suzuki, Kazuo Kobayashi, Hiroshi Ishii, Kunihiko Itoh, Masakazu Yamaguchi, Kenichi Suzuki   +21 more
wiley   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Estimatioin of Origin of White-tailed Eagles that Collide with Wind Turbines During the Wintering Period in Hokkaido, Japan

Пернатые хищники и их охрана, 2018
Approximately 500–1000 White-tailed Eagles (Haliaeetus albicilla) each year winter in Japan. These include both residents breeding in northern Japan and migrants from regions farther north, such as the far-east of Russia. Collision with wind turbines has
Saiko Shiraki, Taro Sugimoto
doaj  

Factors for the Variability of Three Acceptable Maximal Expiratory Flow–Volume Curves in Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2021
Masafumi Yamamoto,1 Satoshi Konno,2 Hironi Makita,2,3 Katsuaki Nitta,4 Kaoruko Shimizu,2 Masaru Suzuki,2 Mutsumi Nishida,1 Junichi Sugita,1 Takanori Teshima,1 Masaharu Nishimura2,3 1Division of Laboratory and Transfusion Medicine, Hokkaido University ...
Yamamoto M, Konno S, Makita H, Nitta K, Shimizu K, Suzuki M, Nishida M, Sugita J, Teshima T, Nishimura M   +9 more
doaj  

CAT‐Hokkaido: A tablet‐based assessment of cognitive impairment in schizophrenia

PCN Reports
Aim Cognitive impairment is a core feature of schizophrenia and is typically assessed using paper‐and‐pencil neuropsychological batteries. However, these traditional methods are time‐consuming and place a substantial burden on examiners before, during ...
Atsuhito Toyomaki, Hayato Watanabe, Ryo Sawagashira, Chiemi Kubota, Naoki Hashimoto, Takahiro A. Kato   +5 more
doaj   +1 more source

Evaluation of High‐Yielding Canadian Soybean Cultivars Suited to Japanese Growing Conditions

Agrosystems, Geosciences & Environment, 2019
Core Ideas Five Canadian soybean cultivars achieved high yields in Hokkaido, northern Japan, in screening tests. OAC Dorado soybean produced a significantly greater yield than a Hokkaido's leading cultivar. OAC Dorado soybean had six characteristics that
Naoya Yamaguchi, Yuho Tsuji, Haruka Suzuki, Takuya Kitabatake, Taiki Yoshihira   +4 more
doaj   +1 more source

Extended survival of Pleistocene Siberian wolves into the early 20th century on the island of Honshū. [PDF]

iScience, 2021
Niemann J, Gopalakrishnan S, Yamaguchi N, Ramos-Madrigal J, Wales N, Gilbert MTP, Sinding MS.   +6 more
europepmc   +1 more source

Vitamin D concentration in maternal serum during pregnancy: Assessment in Hokkaido in adjunct study of the Japan Environment and Children's Study (JECS).

PLoS ONE
BackgroundVitamin D is an essential nutrient for maintaining blood calcium and phosphorus levels and controlling bone density. Deficiency in it leads to rickets, osteomalacia, osteoporosis, and various other diseases.
Ko Nakanishi, Mami Mutoh, Sachiko Itoh, Sumitaka Kobayashi, Takeshi Yamaguchi, Hiroyoshi Iwata, Naomi Tamura, Momoko Koishi, Machiko Kasai, Emi Kikuchi, Nanae Yasuura, Reiko Kishi, Yoshiaki Sato   +12 more
doaj   +1 more source