Results 101 to 110 of about 148,471 (296)

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

A New Nonparasitic Species of the Holarctic Lamprey Genus Lethenteron Creaser and Hubbs, 1922, (Petromyzonidae) from Northwestern North America with Notes on Other Species of the Same Genus [PDF]

, 1978
A new nonparasitic lamprey, Lethenteron alaskense from Alaska and Northwest Territories is described and illustrated. The holotype (No. NMC 76-614) is deposited in the National Museum of Natural Sciences, Ottawa, Canada.
Kott, Edward, Vladykov, Vadim D.
core  

The We‐Relationship as a Key to Addressing Dementia‐Related Ambiguous Loss

Journal of Applied Philosophy, EarlyView.
ABSTRACT Pauline Boss describes the challenges faced by people caring for family members with dementia in terms of ambiguous loss – a condition in which the physical presence of the person with dementia coexists with their psychological absence. This article proposes the concept of we‐relationship as a key to addressing dementia‐related ambiguous loss.
Takuya Niikawa, Xue Li
wiley   +1 more source

Quality-Oriented Technical Change in Japanese Wheat Breeding [PDF]

The article presents a productivity analysis of Japanese Wheat Breeding research. Given recent policy change, wheat breeders may breed high quality, i.e. high protein content, wheat.
Fujii, Yoko, Kondo, Takumi, Osanami, Fumio   +2 more
core   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Population structure of chum salmon (Oncorhynchus keta) across the Pacific Rim, determined from microsatellite analysis [PDF]

, 2009
The Pacific Rim population structure of chum salmon (Oncorhynchus keta) was examined with a survey of microsatellite variation to describe the distribution of genetic variation and to evaluate whether chum salmon may have originated from two or more ...
Beacham, Terry D., Candy, John R., Le, Khai D., Wetklo, Michael   +3 more
core  

Ovulating Female of Nine‐Spined Sticklebacks (Pungitius sinensis) Are Attracted to Substances Derived From Male Kidneys

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Male sticklebacks (Gasterosteidae) produce an adhesive protein called “spiggin” in the tubular epithelial cells of their kidneys, which they use to attach plants or plant debris together and build nesting sites. Spiggin is a glycoprotein excreted in urine.
Miki Nagaya, Hidenobu Yambe, Yasunori Koya   +2 more
wiley   +1 more source

Genetic Diversity of Highly Pathogenic Avian Influenza Viruses Isolated in Hokkaido, Japan, During Winter 2024–2025

Pathogens
Genetic and antigenic analyses were performed on highly pathogenic avian influenza viruses (HPAIVs) isolated in Hokkaido, northern Japan, during the winter of 2024–2025.
Norikazu Isoda, Lim Yik Hew, Kazuki Nishikawa, Fumihito Takaya, Yo Shimazu, Daiki Kobayashi, Kei Nabeshima, Hisako Honjyo, Mana Esaki, Kosuke Okuya, Kosuke Soda, Hiroshi Ito, Asuka Kumagai, Hayate Nishiura, Takahiro Hiono, Hiroki Takakuwa, Tatsufumi Usui, Makoto Ozawa, Yuko Uchida, Manabu Onuma, Yoshihiro Sakoda   +20 more
doaj   +1 more source

Normothermic Machine Perfusion vs. Static Cold Storage for DBD Liver Transplantation in High‐MELD Recipients: A Single‐Center Retrospective Study

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Purpose While normothermic machine perfusion (NMP) has benefits over static cold storage (SCS), its efficacy in high‐acuity recipients with high Model for End‐Stage Liver Disease (MELD) scores, particularly using a back‐to‐base application model, is not well established.
Yuzuru Sambommatsu, Daisuke Imai, Kush Savsani, Mallika Datta, Junpei Tarashi, Jacob Hallesy, Samuel Wolfe, Isao Yokota, Seung Duk Lee, David A. Bruno   +9 more
wiley   +1 more source

PICES Press, Vol. 8, No. 2, July 2000 [PDF]

, 2000
Beyond El Nino Conference The status of the Bering Sea: June - December, 1999 The state of the western North Pacific in the second half of 1999 The state of the eastern North Pacific since autumn 1999 Project Argo Report of the ICES Zooplankton

core