Results 131 to 140 of about 184,302 (306)

The forgotten eruption: global consequences of the 1831 Kuril Islands Zavaritski Caldera in light of eruptions of Tambora (1815) and Pinatubo (1991)

Studia Humanitatis
In summer 1831 the climate in the Northern Hemisphere cooled by an average of about 1 degree Celsius, coinciding with reports of gloomy, harsh weather and the sun changing to different colours.
Christensen Carsten Sander
doaj  

COMPARISON WITH CLIMATE SEVERITY INDEX AND RESULTS BY USING PRINCIPLE COMPONENT ANALYSIS IN CASE OF HOKKAIDO

, 2003
In cold region like Hokkaido, severity index evaluated by weather conditions and sense of climate in each area is required for defining winter's misery.
森, 太郎, 絵内, 正道, 羽山, 広文, 吉原, 美保子, 田村, 佳愛   +4 more
core  

First‐In‐Human Study: Dose Expansion of E7130 in Urothelial Carcinoma and Squamous Cell Carcinoma of the Head and Neck

Cancer Science, EarlyView.
The dose escalation part of the first‐in‐human study of E7130 in patients with advanced solid tumors determined the Recommended Phase 2 Dose of E7130 (480 μg/m2 Q3W). The dose expansion part (presented here) examined safety/preliminary efficacy in patients with squamous cell carcinoma of the head and neck and urothelial carcinoma.
Nobuaki Matsubara, Ken Saijo, Yasushi Shimizu, Susumu Okano, Kenji Nakano, Naoki Nishio, Tomoyuki Otsuka, Hirofumi Kuno, Takuma Miura, Tomoki Kubota, Hiroki Ikezawa, Yuko Umetsu, Ken Ito, Abraham Apfel, Yuanqing Ye, Yoshitaka Honma   +15 more
wiley   +1 more source

Hokkaido Agricultual Guide Lines : To Create a New Agriculture(REPORTS AND DISCUSSION AT THE 82nd MEETING OF THE SOCIETY IN 1991 : The Problems of Farmers in Hokkaido Agriculture)

, 1993
Hokkaido Provincial Govornment planned to use the "Hokkaido Agricultual Guide Lines" to assist farmers in raising their income or reducing their production cost at the time when there is a shortage farmers and part-time workers and government subsidies ...
黒沢, 不二男
core  

Food Habits of Brown Bears in Hokkaido, Japan [PDF]

, 1987
Food habits of the brown bear (Ursus aretos yesoeruis) were studied from 1975 to 1984 in 4 diverse areas on Hokkaido Island. Foods of bears varied seasonally in each area and differed among areas largely because of differences in foods available.
Ohdachi, Satoshi, Aoi, Toshiki
core  

Mutational Signature‐Based Biomarker for Phase II Trial of Olaparib Maintenance in Advanced High‐Grade Ovarian Cancer

Cancer Science, EarlyView.
A whole‐exome sequencing–based mutational signature biomarker (MSBM) identified an HRD‐enriched population in advanced ovarian cancer. In a phase II trial, olaparib maintenance suggested clinically meaningful PFS benefit without bevacizumab, supporting MSBM as a complementary HRD assessment approach.
Katsutoshi Oda, Daisuke Shintani, Akira Nishijima, Mayuyo Mori, Kazuyoshi Kato, Shoji Nagao, Noriomi Matsumura, Masahiro Kagabu, Masataka Takenaka, Kosuke Yoshihara, Yosuke Konno, Junzo Hamanishi, Sho Sato, Shiro Takamatsu, Keiko Ueda, Kosuke Kashiwabara, Takashi Aoki, Kunihiro Nishimura, Kenji Tatsuno, Hiroyuki Aburatani, Kosei Hasegawa   +20 more
wiley   +1 more source

A Floristic Study of Vascular Plants on the Island of Daikoku, Eastern Hokkaido [PDF]

, 2008
A list of vascular plants (ferns, fern allies and seed plants) of the island of Daikoku, Akkeshi town, eastern Hokkaido has been compiled from seven fieldworks done during 2005-2007. It included 189 plant species with one infraspecific taxon. In contrast
Takahashi, Hideki
core  

Family Size and Food Allergy in Early Childhood: The Japan Environment and Children's Study

Allergy, EarlyView.
Takayasu Nomura, Hisashi Tanida, Takeshi Inoue, Sayaka Kato, Daiki Hiraoka, Yuki Ito, Mayumi Sugiura‐Ogasawara, Shinji Saitoh, Michihiro Kamijima, Yukihiro Ohya, The Japan Environment and Children's Study (JECS) Group, Michihiro Kamijima, Shin Yamazaki, Maki Fukami, Reiko Kishi, Chiharu Ota, Koichi Hashimoto, Kenichi Sakurai, Shuichi Ito, Ryoji Shinohara, Hidekuni Inadera, Takeo Nakayama, Ryo Kawasaki, Yasuhiro Takeshima, Hideki Nagashima, Narufumi Suganuma, Mayumi Tsuji, Kimitoshi Nakamura   +27 more
wiley   +1 more source

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

The FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito, Yasuyuki Kitaura, Kyoka Iino, Kazuya Toriumi, Hyunah Noh, Naoya Ogawa, Makoto Arai, Hisashi Hemmi, Tomokazu Ito   +8 more
wiley   +1 more source

Small-Bowel Impaction Caused by Mechanical Interlocking Between Duodenal Metal and Biliary Plastic Stents. [PDF]

DEN Open
ABSTRACT Duodenal self‐expandable metal stents (SEMS) are widely used to treat malignant gastric outlet obstruction (GOO). However, stent migration is a well‐known complication. We report a rare case of small‐bowel impaction caused by the migration of a duodenal SEMS with a biliary plastic stent (PS).
Otagiri S, Sugiura R, Wada M, Nomura A, Egami H, Wakabayashi K, Fujihata K, Katsurada T, Hirano S, Sakamoto N.   +9 more
europepmc   +2 more sources