Results 71 to 80 of about 1,736,490 (289)

Film holder for curved vacuum platen [PDF]

, 1972
Vacuum apparatus for holding photographic film of various widths against cylindrically curved patens is discussed. Construction details and method of operation are explained.
Hauber, C. E., Maciel, A., Jr.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Principal investigator gender and clinical trial success: analysis of over 3000 obstetrics and gynecology trialsAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: In obstetrics and gynecology (OBGYN) research, gender disparities permeate through leadership, funding, promotion, mentorship, publishing, compensation, and publicity.
Jecca R. Steinberg, MD, MSc, Julia D. Ditosto, MS, Brandon E. Turner, MD, MSc, Anna Marie Pacheco Young, MD, MPH, Naixin Zhang, MD, Danielle Strom, MD, Sarah Andebrhan, MD, Madeline F. Perry, MD, Danika Barry, MD, MPH, Kai Holder, MD, Natalie A. Squires, MD, Jill N. Anderson, MD, Michael T. Richardson, MD, Dario R. Roque, MD, Lynn M. Yee, MD, MPH   +14 more
doaj   +1 more source

The study of development of word fluency and conceptual cue task in children with Persian language [PDF]

فصلنامه نوآوری‌های آموزشی, 2008
In the present study, 600 pupils (300 boys and 300 girls) were randomly selected from Tehran elementary schools participating in two perceptual cue task (initial letters) and conceptual cue task (categories).
Reza Kormi Nouri, Alireza Moradi, Saeed Akbari Zardkhanee, Alireza Ghollami   +3 more
doaj  

Tool post modification allows easy turret lathe cutting-tool alignment [PDF]

, 1966
Modified tool holder and tool post permit alignment of turret lathe cutting tools on the center of the spindle. The tool is aligned with the spindle by the holder which is kept in position by a hydraulic lock in feature of the tool post. The tool post is
Fouts, L.
core   +1 more source

Observing the Galactic Plane with the Cherenkov Telescope Array

, 2017
The Cherenkov Telescope Array is a next generation ground-based gamma-ray observatory de- signed to detect photons in the 20 GeV to 300 TeV energy range.
Holder, Jamie, Zanin, Roberta
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source