Results 21 to 30 of about 5,929 (263)
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Holder continuity for vector-valued minimizers of quadratic functionals
In this article we give a sufficient condition for interior everywhere Holder continuity of weak minimizers of a class of quadratic functionals with coefficients $A_{ij}^{\alpha\beta}(\cdot,u)$ belonging to the VMO-class, uniformly with respect to $u\
Josef Danecek, Eugen Viszus
doaj
In this paper, we investigate a class of nonautonomous fractional diffusion equations (NFDEs). Firstly, under the condition of weighted Hölder continuity, the existence and two estimates of classical solutions are obtained by virtue of the properties of ...
Jia Mu, Yang Liu, Huanhuan Zhang
doaj +1 more source
Holder Continuity of Quasiconformal Mappings of the Unit Ball [PDF]
The authors obtain a modified form of Gehring’s Hölder-continuity theorem for the family of K K -quasiconformal self ...
Anderson, G. D., Vamanamurthy, M. K.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An alternative approach to partial regularity of quasilinear elliptic systems with VMO coefficients
In this paper, we provide an alternative approach to partially Hölder continuity of some quasilinear elliptic systems with discontinuous coefficients under natural growth.
Haiyan Yu, Shenzhou Zheng, Yuxia Tong
doaj +1 more source
Gradient estimates for the fundamental solution of Lévy type operator
We prove a gradient estimate and the Hölder continuity of the gradient for the fundamental solution of a class of α-stable type operators with α ∈ (0, 1), which improve known results in the literature where the condition α > 1/2 is commonly assumed.
Liu Wei, Song Renming, Xie Longjie
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

