Results 41 to 50 of about 516,056 (300)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Persistence of Holder continuity for non-local integro-differential equations
, 2015 In this paper, we consider non-local integro-differential equations under certain natural assumptions on the kernel, and obtain persistence of Holder continuity for their solutions. In other words, we prove that a solution stays in C-beta for all time if
Kyudong Choi, Choi, Kyudong
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hölder Continuity of Solutions to Parametric Generalized Vector Quasiequilibrium Problems
Abstract and Applied Analysis, 2012 By using a linear scalarization method, we establish sufficient conditions for the Hölder continuity of the solution mappings to a parametric generalized vector quasiequilibrium problem with set-valued mappings.
Z. Y. Peng
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Weaker forms of continuity [PDF]
, 1972 This paper is concerned with a study of various weaker forms of continuity. The definitions originated in [1], [2], and [4] . In Chapter I, the definitions of several types of continuity are given and examples are given to show that these are actually ...
Keith, Martha Allred +1 more
core
On Holder continuity of solution maps of parametric primal and dual Ky Fan inequalities
, 2015 We consider parametric primal and dual Ky Fan inequalities in metric linear spaces. Sufficient conditions for Holder continuity of solutions are established.
Anh, Lam Quoc +2 more
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Continuous Sharpening of Hölder's and Minkowski's Inequalities [PDF]
Mathematical Inequalities & Applications, 2005 Some properties of functions which in special cases lead to sharpening of Holder's and other interesting inequalities are proved. Results analogue to theorems leading to reverse Holder's inequality are presented.
Abramovich, S. +2 more
openaire +3 more sources