Results 51 to 60 of about 164,762 (278)

Hölder Continuity of Solutions to Parametric Generalized Vector Quasiequilibrium Problems

Abstract and Applied Analysis, 2012
By using a linear scalarization method, we establish sufficient conditions for the Hölder continuity of the solution mappings to a parametric generalized vector quasiequilibrium problem with set-valued mappings.
Z. Y. Peng
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Valuations and plurisubharmonic singularities

, 2007
We extend to higher dimensions some of the valuative analysis of singularities of plurisubharmonic (psh) functions developed by the last two authors. Following Kontsevich and Soibelman we describe the geometry of the space V of all normalized valuations ...
Boucksom, Sebastien, Favre, Charles, Jonsson, Mattias   +2 more
core   +5 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

HOLDER CONTINUOUS FUNCTIONS AND THEIR ABEL AND LOGARITHMIC MEANS

Tamkang Journal of Mathematics, 1999
Mahapatra and Chandra [8] have obtained the degree of approximation for $f \in H_\alpha(0\le \beta<\alpha\le 1)$ using infinite matrix $A = (a_{nk})$. Mahapatra and Chandra [7] used Euler, Boral and Taylor means. In the present paper we have obtained the analogous results using Abel ($A_\lambda$) and Logarithmic ($L$)-means ...
Sharma, Sushil, Varma, S. K.
openaire   +3 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Holder continuity of bounded weak solutions to generalized parabolic p-Laplacian equations I: degenerate case

Electronic Journal of Differential Equations, 2015
Here we generalize quasilinear parabolic p-Laplacian type equations to obtain the prototype equation $$ u_t - \hbox{div} \Big(\frac{g(|Du|)}{|Du|} Du\Big) = 0, $$ where g is a nonnegative, increasing, and continuous function trapped in between two
Sukjung Hwang, Gary M. Lieberman
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Monotone iterative technique for finite systems of nonlinear Riemann-Liouville fractional differential equations [PDF]

Opuscula Mathematica, 2011
Comparison results of the nonlinear scalar Riemann-Liouville fractional differential equation of order \(q\), \(0 \lt q \leq 1\), are presented without requiring Hölder continuity assumption.
Z. Denton, A. S. Vatsala
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source