Results 61 to 70 of about 164,762 (278)

Holder continuity for a periodic 2-component mu-b system

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we consider the Cauchy problem of a periodic 2-component $\mu$-b system. We show that the date to solution for the periodic 2-component $\mu-b$ system is Holder continuous from bounded set of Sobolev spaces with exponent s>5/2 ...
Xiaohuan Wang
doaj  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Holder regularity for signed solutions to singular porous medium type equations

open access: yesElectronic Journal of Differential Equations, 2012
We prove Holder regularity for bounded signed solution to singular porous medium type equations, whose prototype is $$ u_t-hbox{div}m|u|^{m-1}Du=0quadhbox{weakly in }E_T, $$ with $min(0,1)$.
Simona Puglisi
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The Holder continuity of the swirl for the Navier-Stokes motions

open access: yes, 2012
Applying the DeGiorgi Method the Holder continuity of the swirl is proved for solutions to the Navier-Stokes equations from Lq(0,T;Lp) with 3/p+2/q < 1.
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Hölder continuity of solutions for some Schrödinger equations(一类Schrödinger方程解的Hölder连续性)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2000
本文证明了Schrödinger方程Lu≡Au+b·∇u+Vu=0的弱解的Hölder连续性,其中A为二阶散度型一致椭圆算子,|b|2,V∈L1,λ(n ...
CHENYe-min(陈晔愍)
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Harnack inequality for a class of functionals with non-standard growth via De Giorgi’s method

open access: yesAdvances in Nonlinear Analysis, 2018
We study the regularity theory of quasi-minimizers of functionals with Lp⁢(⋅)⁢log⁡L{L^{p(\,\cdot\,)}\log L}-growth. In particular, we prove the Harnack inequality and, in addition, the local boundedness and the Hölder continuity of the quasi-minimizers ...
Ok Jihoon
doaj   +1 more source

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