Results 71 to 80 of about 5,929 (263)
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Boundedness and Hölder continuity of weak solutions of the nonlinear boundary-value problem for elliptic equations with general nonstandard growth conditions [PDF]
Mathematica BohemicaWe study a nonlinear boundary-value problem for elliptic equations with critical growth conditions involving Lebesgue measurable functions. We prove global boundedness and Hölder continuity of weak solutions for this problem.
Gumpyong Ri, Dukman Ri
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2004 We obtain global estimates for the modulus, interior gradient estimates, and boundary Hölder continuity estimates for solutions u to the capillarity problem and to the Dirichlet problem for the mean curvature equation merely in terms of the mean ...
Fei-Tsen Liang
doaj +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Vector-valued Morrey's embedding theorem and Holder continuity in parabolic problems
Electronic Journal of Differential Equations, 2011 If $Isubset mathbb{R}$ is an open interval and $Omega subset mathbb{R}^N$ an open subset with $partial Omega $ Lipschitz continuous, we show that the space $W^{1,p}(I,L^q (Omega ))cap L^p(I,W^{1,q}(Omega ))$ is continuously embedded in $C^{0,frac{1 ...
Patrick J. Rabier
doaj
A Note on Hölder Continuity of Solution Set for Parametric Vector Quasiequilibrium Problems
Abstract and Applied Analysis, 2011 By using a scalarization technique, we extend and sharpen the results in S. Li and X. Li (2011) on the Hölder continuity of the solution sets of parametric vector equilibrium problems to the case of parametric vector quasiequilibrium problems in ...
Xian-Fu Hu
doaj +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
Міжнародний науково-технічний журнал "Проблеми керування та інформатики"One of the most important problems of applied mathematics is the study of various problems of natural science, which ultimately leads to the compilation of mathematical models of the phenomena under study.
Ю.І. Харкевич
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source