Results 51 to 60 of about 72,792 (298)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

A New Behavioral Model of Gate-Grounded NMOS for Simulating Snapback Characteristics

open access: yesIEEE Access, 2020
A new behavioral model of gate-grounded NMOS (ggNMOS) device is proposed for electrostatic discharge (ESD) simulation of snapback behavior. The concise snapback model is a solution for the lack of snapback characteristics of build-in SPICE models in high
Yize Wang, Guangyi Lu, Yuan Wang
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Schottky-Embedded Isolation Ring to Improve Latch-Up Immunity Between HV and LV Circuits in a 0.18 μm BCD Technology

open access: yesIEEE Journal of the Electron Devices Society, 2022
As the high-voltage (HV) and low-voltage (LV) circuits are integrated together in a common silicon substrate, the parasitic latch-up path between neighboring HV and LV circuits with limited spacing in layout would be triggered into latch-up state to ...
Zi-Hong Jiang, Ming-Dou Ker
doaj   +1 more source

GHB has no effect on the holding current of voltage clamped neurons.

open access: yes, 2013
A1, Mean holding current over time in response to the application of GHB in VB thalamic neurons (n = 6). Grey area shows SEM. Left inset, representative image of a VB neuron. Scale bar 50 µm. Right inset, voltage response of a representative VB neuron to
William M. Connelly (482876)   +2 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Design and Analysis of an Area-Efficient High Holding Voltage ESD Protection Device

open access: yes, 2015
A novel electrostatic discharge protection device gate-grounded nMOS (GGnMOS) incorporated silicon-controlled rectifier (GGISCR) is proposed in this paper.
Zeng, Jie   +4 more
core   +2 more sources

ESM-Regio: simulation and optimization of regional energy systems in carbon-neutral scenarios

open access: yesEnergy Informatics
This work presents a high-resolution, sector-coupled energy system modeling framework developed within the research project ESM-Regio, designed to analyze regional energy transitions and the sector coupling potential in the context of Germany’s 2045 ...
Kevin-Martin Aigner   +15 more
doaj   +1 more source

Control of Slc7a5 sensitivity by the voltage-sensing domain of Kv1 channels

open access: yeseLife, 2020
Many voltage-dependent ion channels are regulated by accessory proteins. We recently reported powerful regulation of Kv1.2 potassium channels by the amino acid transporter Slc7a5. In this study, we report that Kv1.1 channels are also regulated by Slc7a5,
Shawn M Lamothe   +7 more
doaj   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

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