Results 81 to 90 of about 72,792 (298)

Rc-Embedded Ldmos-Scr With High Holding Current For High-Voltage I/O Esd Protection

open access: yes, 2015
A novel lateral diffusion MOS-embedded silicon-controlled rectifier with a high holding current (LDMOS-SCR-HHC) is proposed and verified in a 0.25-μ m 18-V Bipolar-CMOS-DMOS process. By adding an imbedded P+ region located next to the source region of an
Gu, Xiaofeng   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Holding potential affects the apparent voltage-sensitivity of sodium channel activation in crayfish giant axons

open access: yes, 1990
Sodium channel activations, measured as the fraction of channels open to peak conductance for different test potentials (F[V]), shows two statistically different slopes from holding potential more positive than -90 mV. A high valence of 4–6e is indicated
Ruben, P.C., Rayner, M.D., Starkus, J.G.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Dynamic Modulation of OECT‐Based Inverters for In Situ Electrophysiological Monitoring

open access: yesAdvanced Science
Organic electrochemical transistors (OECTs) and their related circuits have emerged as a promising platform for biosensors and neuromorphic electronics, benefiting from their sub‐1 V operation voltage, flexibility, biocompatibility, etc.
Guohong Hu   +7 more
doaj   +1 more source

Zero-current Zero-voltage Transition Pwm Converters With Magnetically Coupled Auxiliary Circuit

open access: yesEletrônica de Potência, 2008
This paper presents a novel methodology to synthesize Zero-Current Zero-Voltage Transition (ZCZVT) topologies. The proposed methodology is based on the Auxiliary Voltage Source (AVS) concept, which permits extend the proposed new circuits to an entire ...
Mário L. da S. Martins   +3 more
doaj   +1 more source

The design of high holding voltage SCR for whole-chip ESD protection

open access: yesIEICE Electronics Express, 2008
In this paper, we have investigated the electrical characteristics of Silicon Controlled Rectifier (SCR)-based ESD power clamp circuit with high holding voltage for whole-chip ESD protection. The proposed ESD power clamp circuit (HHVSCR: High Holding Voltage SCR) has different well (n/p-well) length (3/7µm - 8/2µm) and p-drift (p+) length (8µm - 16µm).
Koo, Yong-Seo   +3 more
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Silicon-Controlled Rectifier Stacking Structure for High-Voltage ESD Protection Applications

open access: yes, 2010
Latchup immunity is a challenging issue for the design of power supply clamps used in high-voltage electrostatic discharge (ESD) protection applications. While silicon-controlled rectifiers (SCRs) are highly robust ESD devices, they are traditionally not
null Zhiwei Liu   +7 more
core   +2 more sources

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