Results 131 to 140 of about 6,154 (303)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

[News Clip: Skillerns Holdup]

open access: yes, 1960
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a robbery at The Skillerns Drugstore in Oak Cliff ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Holdup data analysis for Portsmouth Building X705 [PDF]

open access: yes, 1991
The Portsmouth Gaseous Diffusion Plant's Building X705 contains equipment for recovering uranium from other facility process equipment and materials. Measurements of holdup have been made at 825 locations within the building, including tanks, columns ...
Thomas, K.E.   +4 more
core  

ESTIMATION OF GAS HOLDUP AND INPUT POWER IN FROTH FLOTATION USING ARTIFICIAL NEURAL NETWORK

open access: yesIranian Journal of Materials Science and Engineering, 2015
Multivariable regression and artificial neural network procedures were used to modeling of the input power and gas holdup of flotation. The stepwise nonlinear equations have shown greater accuracy than linear ones where they can predict input power, and ...
B. Shahbazi   +4 more
doaj  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Holdup measurement for nuclear fuel manufacturing plants [PDF]

open access: yes, 1981
The assay of nuclear material holdup in fuel manufacturing plants is a laborious but often necessary part of completing the material balance. A range of instruments, standards, and a methodology for assaying holdup has been developed.
Cohen, I.   +7 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

The Morphology of Trickle Flow Liquid Holdup [PDF]

open access: yes, 2005
Dissertation (MEng)--University of Pretoria, 2004.Gravity driven trickle flow of a liquid over a fixed bed in the presence of a gaseous phase is widely encountered throughout the process industry.

core  

[News Clip: Two admit holdup]

open access: yes, 1958
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about Hugo C.
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

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