Results 51 to 60 of about 19,838 (208)

Medicinal plant-derived mtDNA via nanovesicles induces the cGAS-STING pathway to remold tumor-associated macrophages for tumor regression

Journal of Nanobiotechnology, 2023
Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the inter-kingdom interaction and communication, but the effector components enclosed in the vesicles and the mechanisms involved are largely unknown.
Jinfeng Liu, Jiaxin Xiang, Cuiyuan Jin, Lusha Ye, Lei Wang, Yanan Gao, Nianyin Lv, Junfeng Zhang, Fuping You, Hongzhi Qiao, Liyun Shi   +10 more
doaj   +1 more source

Benchmarking Coaxial and Angular Optical Emission Spectroscopy With Recommendations for Reliable Compositional In Situ Monitoring During Laser Powder Bed Fusion

Advanced Materials Technologies, EarlyView.
ABSTRACT Real‐time insight into local chemistry is critical for reliable part quality in additive manufacturing, especially laser powder bed fusion (PBF‑LB/M), where rapid thermal cycles and localized evaporation can undermine part performance. Optical emission spectroscopy (OES) offers non‑intrusive, in situ plume monitoring, but detection geometry ...
Philipp Gabriel, Bastian Jülich, Anna Rosa Ziefuss, Florian Eibl, Stephan Barcikowski   +4 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Dihydroartemisinin Induces Growth Arrest and Overcomes Dexamethasone Resistance in Multiple Myeloma

Frontiers in Oncology, 2020
The discovery of artemisinin (ART) for malaria treatment won the 2015 Nobel Prize in Medicine, which inspired the rediscovery and development of ART for the treatment of other diseases including cancer.
Ying Chen, Ying Chen, Rui Li, Yuqi Zhu, Yuqi Zhu, Sixia Zhong, Jinjun Qian, Dongqing Yang, Artur Jurczyszyn, Meral Beksac, Chunyan Gu, Chunyan Gu, Ye Yang, Ye Yang   +13 more
doaj   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

The “Treatise on the spleen and stomach” (Pí Wèi Lùn) as the first record of multiple sclerosis in the medical literature – A hypothesis based on the analysis of clinical presentation and herbal medicine

Journal of Traditional and Complementary Medicine, 2020
Background: The “Treatise on the spleen and stomach” (Pí Wèi Lùn) is the work of the scholar and physician Li Gao (Jin-Yuan dynasties, 1115–1368 C.E., China).
Andréa D. Fuzimoto, Francesco Brigo
doaj   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

Advanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang, Zixuan Zhang, Bingyan Li, Junkai Wang, Hongcheng Gu   +4 more
wiley   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

Advanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu, Bin Cui, Xumin Huang, Xiaoyu (Rayne) Zheng, T. Thang Vo‐Doan, Ruirui Qiao   +5 more
wiley   +1 more source

Intelligent Maintenance Review for Robots: Multimodal Information, Deep Diagnosis and Embodied Artificial Intelligence

Advanced Robotics Research, EarlyView.
This review maps the methods to monitor robots’ health by fusing vibration, sound, control signals, vision, force, and oil information with artificial intelligence. It identifies deep learning, transfer learning, digital twins, and physics‐informed models as key methodological pathways enabling earlier diagnosis, safer human–robot collaboration, and ...
Yuting Qiao, Hongbo Wang, Naipeng Li, Shuo Wang, Yaguo Lei, Tonghai Wu, Junyi Cao   +6 more
wiley   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source