Results 131 to 140 of about 293,402 (335)
Journal of Human Rights and the Environment, 2019 We are now accustomed to thinking of the Holocene as an epoch that we have left behind. But from what perspective do we close the Holocene and begin describing the Anthropocene? Academic disciplines have their own geology: epistemic or medial strata, sediments or condensations, which condition the apprehension and communication of fresh insight.
openaire +2 more sources
The Holocene, 2019 This synthesis paper offers a comparative perspective on how seven different Mediterranean regions, from Iberia and Morocco to the Levant, have been transformed by human and natural agencies during the past 10 millennia.
C. Roberts +6 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Postglacial relative sea level change at Fildes Peninsula, King George Island (West Antarctic)
Лëд и снег, 2016 Analysis and integration of data obtained in our field and laboratory investigations of 2008–2012 together with results of previous paleogeographic studies were conducted to reveal parameters and factors of the post-glacial changes in the relative sea ...
K. V. Polishchuk +3 more
doaj +1 more source
Quaternary Science Reviews, 2019 The effective humidity, resulting from the balance between evapotranspiration and precipitation, largely controls the environmental conditions under the highly continental, semi-humid to arid climate of Mongolia.
M. Klinge, D. Sauer
semanticscholar +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Журнал Белорусского государственного университета: География, геология, 2017 In the article are set forth materials of the palynological researches of the soil sediments in the section et the vil. Stajki (Mogilev Podniepr, Belarus), the age of which is dated Holocene interglacial (isotopic stage 1). Characterized spectra clearing
Yadviga K. Yelovicheva
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source