Results 171 to 180 of about 240,870 (365)
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Palynology and sedimentology of Holocene deposits in southern Lake Michigan /
James E. King +2 more
openalex +2 more sources
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Holocene Climatic Change in the Lowland Area of North of Sapporo, Japan
Yaeko Igarashi, S. Kumano
openalex +2 more sources
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
A. Area of Scandinavian Glaciation: 1. Pleistocene and Holocene
Klaus Duphorn +4 more
openalex +1 more source
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Major periods of erosion and alluvial sedimentation in New Zealand during the Late Holocene [PDF]
Patrick Grant
openalex +1 more source
Holocene peat in the Netherlands
Peat comes in many kinds. Within the Holocene of the Netherlands, various types of deltaic, coastal and lagoonal peat are recognised. Over adjacent inlands even more types are known. We can look at them with ecological eyes (plant species, nutrient availability), hydrological eyes (maintaining their own local groundwater table, or obeying a regional ...
openaire +3 more sources

