Results 221 to 230 of about 2,375 (233)

The Usefulness of Holotranscobalamin in Predicting Vitamin B12 Status in Different Clinical Settings

Current Drug Metabolism, 2005
Serum concentrations of homocysteine (Hcy) and methylmalonic acid (MMA) become increased in B12-deficient subjects and are therefore, considered specific markers of B12 deficiency. Serum level of holotranscobalamin (holoTC) becomes decreased before the development of the metabolic dysfunction.
Wolfgang, Herrmann, Rima, Obeid, Heike, Schorr, Jürgen, Geisel   +3 more
openaire   +2 more sources

Low holotranscobalamin and cobalamins predict incident fractures in elderly men: the MrOS Sweden

Osteoporosis International, 2013
In a population-based study on cobalamin status and incident fractures in elderly men (n = 790) with an average follow-up of 5.9 years, we found that low levels of metabolically active and total cobalamins predict incident fractures, independently of body mass index (BMI), bone mineral density (BMD), plasma total homocysteine (tHcy), and cystatin C ...
Lewerin, C. Lewerin, Nilsson-Ehle, H., Jacobsson, S., Johansson, Helena, Sundh, V., Karlsson, Magnus, Ljunggren, Östen, Lorentzon, Mattias, Kanis, John A., Lerner, Ulf H., Cummings, Steven R., Ohlsson, Claes, Mellström, Dan   +12 more
openaire   +4 more sources

The importance of active B12 (holotranscobalamin) measurement in the diagnosis of vitamin B12 deficiency in type 2 DM patients using metformin

International Journal of Diabetes in Developing Countries, 2023
T. Yıldız, Sevval Yıldız, Muhammed Tunc, Ozge Pasin, Caner Yıldız, Mustafa Çakırca, C. Karatoprak, O. Ozer   +7 more
semanticscholar   +1 more source

Corrigendum to "Reference intervals and stability of haptocorrin and holotranscobalamin in Danish children and elderly" [Clin. Chim. Acta 546 (2023) 117394].

Clinica chimica acta; international journal of clinical chemistry, 2023
C. S. Knudsen, T. Parkner, Elke Hoffmann-Lücke, A. Abildgaard, Eva Greibe   +4 more
semanticscholar   +1 more source

Comparison of Serum Holotranscobalamin with Serum Vitamin B12 in Population Prone to Megaloblastic Anemia and their Correlation with Nerve Conduction Study

Indian Journal of Clinical Biochemistry, 2022
A. Verma, S. Aggarwal, S. Garg, S. Kaushik, D. Chowdhury   +4 more
semanticscholar   +1 more source

Holotranscobalamin--a first choice assay for diagnosing early vitamin B deficiency?

Journal of internal medicine, 2005
The performance of holotranscobalamin (holoTC) was compared with the other markers of vitamin B12 deficiency, and the influence of age, renal function, and thyroid status was examined.We examined 937 individuals not treated with vitamin B12 but in whom vitamin B12 deficiency was suspected because of a plasma methylmalonic acid (MMA) above 0.28 micromol
Hvas, Anne-Mette, Nexo, E
openaire   +2 more sources

Serum holotranscobalamine, vitamin B12, folic acid and homocysteine levels in patients with vitiligo.

Clinical and experimental dermatology, 2012
Few studies have investigated the role of vitamin B12 metabolism in vitiligo. We tested the hypothesis that vitamin B12 and folate metabolism might have an influence on the pathogenesis of vitiligo. Full blood count and levels of folic acid, vitamin B12, homocysteine and holotranscobalamine were examined for 69 patients with vitiligo and 52 controls ...
Ertugrul, D. T., Tutal, E., Karadag, A. S., Akin, K. O., Bilgili, Serap   +4 more
openaire   +2 more sources

Holotranscobalamin as an indicator of vitamin B12 deficiency in gastrectomized patients.

Annals of clinical and laboratory science, 2013
Transcobalamin-bound vitamin B(12), or holotranscobalamin (HoloTC), a biologically active form, is believed to be a sensitive marker of vitamin B(12) deficiency. We investigated the prevalence of vitamin B(12) deficiency in gastrectomized patients using HoloTC and total vitamin B(12) to determine the diagnostic utility of HoloTC.
Young Kyung, Lee, Han-Sung, Kim, Hee Jung, Kang   +2 more
openaire   +1 more source

Molecular imprinting based electrochemical sensor for determination of vitamin B12 using holotranscobalamin as biomarker

Microchemical journal (Print)
Rishika Rohilla, Ankit, Amandeep Kaur, N. Prabhakar   +3 more
semanticscholar   +1 more source

Au@Pt Nanoparticles as Catalysts for the Detection of Holotranscobalamin as a Biomarker for Vitamin B12 Deficiency

ACS Applied Nano Materials
Rishika Rohilla, Surbhi Kumari, Sonia Rani, N. Prabhakar   +3 more
semanticscholar   +1 more source