Results 1 to 10 of about 390 (152)

Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins’ Synthesis in Solid Cancers [PDF]

Nutrients, 2022
Cobalamin or vitamin B12 (B12) is a cofactor for methionine synthase and methylmalonyl-CoA mutase, two enzymes implicated in key pathways for cell proliferation: methylation, purine synthesis, succinylation and ATP production. Ensuring these functions in
Geoffrey Urbanski, Guy Lenaers, Valentin Lacombe   +2 more
exaly   +4 more sources

Hypervitaminemia B12 in the elderly: a forgotten marker of serious underlying diseases [PDF]

European Journal of Case Reports in Internal Medicine
Hypervitaminemia B12, long neglected in clinical practice, is a biological anomaly whose pathological significance remains largely underestimated, particularly in the elderly.
Abrar-Ahmad Zulfiqar
doaj   +2 more sources

Vitamin B12 Pharmaconutrition for COVID-19 [PDF]

Revista de Nutrición Clínica y Metabolismo, 2020
Mortality from COVID-19 disease is much greater in the elderly, many of whom succumb to acute respiratory distress syndrome (ARDS) triggered by the viral infection.
William Manzanares, Gil Hardy
doaj   +2 more sources

A80G polymorphism of reduced folate carrier 1 (RFC1) and C776G polymorphism of transcobalamin 2 (TC2) genes in Down's syndrome etiology

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: There is evidence that polymorphisms of genes involved in folate metabolism may be associated with higher risk that mothers may bear a Down's syndrome (DS) child.
Joice Matos Biselli, Daniela Brumati, Vivian Fernanda Frigeri, Bruna Lancia Zampieri, Eny Maria Goloni-Bertollo, Érika Cristina Pavarino-Bertelli   +5 more
doaj   +1 more source

Transcobalamin II Deficiency in an Infant with a Novel Mutation. [PDF]

Turk Arch Pediatr, 2022
Toret E, Özdemir ZC, Bor Ö.
europepmc   +1 more source

Diagnostic reliability of serum active B12 (holo-transcobalamin) in true evaluation of vitamin B12 deficiency: Relevance in current perspective. [PDF]

BMC Res Notes, 2022
Dastidar R, Sikder K.
europepmc   +1 more source

Clinical Pathobiochemistry of Vitamin B₁₂ Deficiency: Improving Our Understanding by Exploring Novel Mechanisms with a Focus on Diabetic Neuropathy. [PDF]

Nutrients, 2023
Schleicher E, Didangelos T, Kotzakioulafi E, Cegan A, Peter A, Kantartzis K.   +5 more
europepmc   +1 more source

A novel TCN2 mutation with unusual clinical manifestations of hemolytic crisis and unexplained metabolic acidosis: expanding the genotype and phenotype of transcobalamin II deficiency. [PDF]

BMC Pediatr, 2022
Pongphitcha P, Sirachainan N, Khongkraparn A, Tim-Aroon T, Songdej D, Wattanasirichaigoon D.   +5 more
europepmc   +1 more source

The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the muscle-gut-brain axis and implications for SARS-CoV-2 infection. [PDF]

Nutr Rev, 2022
Batista KS, Cintra VM, Lucena PAF, Manhães-de-Castro R, Toscano AE, Costa LP, Queiroz MEBS, de Andrade SM, Guzman-Quevedo O, Aquino JS.   +9 more
europepmc   +1 more source

Persistent hypercobalaminemia three months after successful gradual attenuation of extrahepatic shunts in dogs: a prospective cohort study. [PDF]

BMC Vet Res, 2022
Devriendt N, Serrano G, Paepe D, Vandenabeele S, Stock E, de Rooster H.   +5 more
europepmc   +1 more source