Results 31 to 40 of about 390 (152)

Vitamin B12 and Reproductive Health: Clinical Insights, Emerging Mechanistic Understanding, and Nutritional Aspects

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Epidemiological data from assisted reproductive technologies (ART) link vitamin B12 (VitB12) deficiency to shorter gestation, low birth weight, and reduced live birth rates. VitB12 also plays a critical role in fertility for both sexes by supporting gamete quality.
Aimee Rachel Mathew, Erisa Selita, Chiara Regano, Claudia Bianco, Veronica Corsetti, Virve Cavallucci, Sandra Moreno, Ada Maria Tata, Marco Fidaleo   +8 more
wiley   +1 more source

Transcobalamin II-mediated uptake of vitamin B12 by rat liver cells [PDF]

, 1979
Vitamin B12 plays a unique role in mammalian metabolism not only because, as a coenzyme, it is involved in two completely different and unrelated biochemical pathways, - the synthesis of nucleic acid precursors and the catabolism of some fatty acids ...
Lindemans, J. (Jan)
core   +1 more source

Neurological diagnoses in children potentially fulfilling the criteria for developmental coordination disorder

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 251-262, February 2026.
In children potentially fulfilling the criteria for developmental coordination disorder (DCD), phenotypical assessment does not sufficiently predict the diagnostic outcome (i.e. DCD or an alternative diagnosis). Due to the lack of distinguishing clinical and diagnostic features and the high prevalence of genetic diagnoses in these patients, additional ...
Martinica Garofalo, Fleur Vansenne, Jessika F. van Hoorn, Marina A. J. Tijssen, Dineke S. Verbeek, Deborah A. Sival   +5 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

KCTD5::PDGFRB Fusion Gene Leading to Clonal Hypereosinophilia With Cardiac Involvement in a Young Adult: A Case Report

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Hypereosinophilia may be the presenting feature of various conditions, including myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions (MLN‐eo‐TK). We report the case of a 22‐year‐old male presenting with chest pain and severe cardiac involvement in the setting of marked hypereosinophilia.
Léona de Groote, Daphné Papazoglou, Jade Ku, Pierre Heimann, Laurent Dewispelaere, Pierre Sidon, Florence Roufosse, Anne-Laure Trépant, Nicolas Cilla, Kalyani Sen   +9 more
wiley   +1 more source

Gießener Vollwert-Ernährungs-Studie Teil II : Einfluß der Kostform auf den Vitamin-B12- und Folatstatus in der Schwangerschaft [PDF]

, 2000
Fragestellung: Hat die Kostform einen Einfluß auf den Vitamin-B12- und Folatstatus in der Schwangerschaft? Kann die Vollwert-Ernährung auchfür schwangere Frauen eine ausreichende Versorgung gewährleisten?
Koebnick, Corinna
core   +1 more source

Elevated Serum Vitamin B12 Levels as a Potential Biomarker for Solid Tumors in Jordanian Patients: A Retrospective Case–Control Study

International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Background Vitamin B12 deficiency is classically associated with anemia and neurological dysfunction. However, recent studies suggest that elevated plasma vitamin B12 may indicate increased short‐term cancer risk. This association remains largely unexplored in Middle Eastern populations, including Jordan, where cancer rates are rising and diagnosis ...
Sahar Kamal Otoom, Lobna Gharaibeh, Anas Abed, Ibrahim Aldeeb, Osamu Ishibashi   +4 more
wiley   +1 more source

The transcobalamin receptor, redux

Blood, 2009
Cobalamin (Cbl; B12) is an essential micronutrient required by all cells in the body. For several decades, we have been aware that Cbl-binding proteins escort B12 to sites of absorption and cellular uptake. Thus, intrinsic factor (IF), with its high-binding specificity for Cbl, mediates the absorption of B12 in the gut. The distribution and delivery of
Donald W. Jacobsen, Alla V. Glushchenko
openaire   +2 more sources

Unveiling Nutritional Disparities in Infantile Tremor Syndrome: A Focus on Holo‐Transcobalamin and Essential Fatty Acids

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Infantile tremor syndrome (ITS), a self‐limiting disorder prevalent in the Indian subcontinent, is characterized by tremors, anemia, pigmentary skin changes, developmental delay or regression, and hypotonia. Although a nutritional etiology is suspected, particularly vitamin B12 deficiency, the roles of the bioactive marker holo‐transcobalamin (holo‐TC)
Rajesh Gupta, Puneet Agrawal, Jyoti Gupta, Jyoti Singh, Ashish Pathak, Priya Gusain   +5 more
wiley   +1 more source

Vitamin‐Engineered Nanoplatforms in Precision Oncology: Integrating Immunotherapy, Delivery Systems, and Theranostics

MedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.
Vitamin‐derived nanoplatforms advance precision oncology by augmenting immunotherapy through dendritic cell activation, T‐cell reprogramming, and TME remodeling to enhance antitumor immunity, while enabling targeted therapeutic delivery. These systems integrate theranostic capabilities using vitamin‐conjugated imaging probes for concurrent tumor ...
Ruowa Xu, Yunlong Gao, Hailong Zhang, Zichao Luo   +3 more
wiley   +1 more source