Results 151 to 160 of about 58,381 (260)

Effects of reducing sedentary behaviour on heart rate variability and cardio‐metabolic biomarkers in desk workers with untreated high blood pressure

Experimental Physiology, EarlyView.
Abstract Lower sedentary behaviour (SB) has been associated with reduced cardiovascular disease and mortality. Yet, few trials have evaluated cardiovascular mechanisms of benefit. We examined the effects of a SB reduction intervention on heart rate variability (HRV) and cardio‐metabolic biomarkers.
Abdullah Bandar Alansare, Matthew F. Muldoon, Subashan Perera, Kimberly A. Huber, Molly B. Conroy, John M. Jakicic, Bethany Barone Gibbs   +6 more
wiley   +1 more source

HOMA-IR partially mediates the association between percent appendicular skeletal muscle mass and IVF/ICSI outcomes. [PDF]

J Ovarian Res
Ni D, Wang X, Zheng Z, Yu K, Xie Q, Zhao C, Ling X, Yang Y.   +7 more
europepmc   +1 more source

Women with a history of gestational diabetes mellitus have preserved sensory nerve‐mediated dilatation in the cutaneous microvasculature

Experimental Physiology, EarlyView.
Abstract Women with a history of gestational diabetes mellitus (GDM) have a greater risk of developing type 2 diabetes mellitus and cardiovascular disease than healthy control (HC) women who had an uncomplicated pregnancy. Microvascular endothelial dysfunction, mediated by reduced nitric oxide (NO)‐dependent mechanisms, persists after GDM.
Grace S. Maurer, Kelsey S. Schwartz, Diana I. Jalal, Anna E. Stanhewicz   +3 more
wiley   +1 more source

The overlooked biochemical pathway: how insulin resistance (HOMA-IR) modulates "metabolic masking" of prostate-specific antigen separately from body mass index. [PDF]

Int Urol Nephrol
Eren MT, Özveri H.
europepmc   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

The ALT/AST Ratio as a Predictor of MASLD in Obese Children: A Comparative Analysis with Metabolic Indices Including HOMA-IR and TyG. [PDF]

J Clin Med
Kabukçu HO, Hazer İ.
europepmc   +1 more source

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

The Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul, Boglarka Nagy, Sofia Laforest, Joanna P. Simpson, William Mungall, Natalie Z. M. Homer, Robert K. Semple, Ruth Andrew, Roland H. Stimson, Mark Nixon   +9 more
wiley   +1 more source

Relationship of HOMA-IR with chronic kidney disease in diabetic and non-diabetic Chinese populations: findings from the REACTION study. [PDF]

Front Endocrinol (Lausanne)
Liao Y, Guan M, Wan Q, Song H, Hu H.
europepmc   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

Correction: MAFLD is associated with lower bone mineral density in patients with type 2 diabetes: an exploratory cross-sectional analysis of a potential indirect association with HOMA-IR. [PDF]

Front Med (Lausanne)
Lin L, Zhuang Y, Xu R, Yi W, Chen P, Wang W.   +5 more
europepmc   +1 more source