Results 31 to 40 of about 230,540 (244)

Subdiagnóstico de la fibromialgia en hombres: revisión de la literatura y reporte de un caso

open access: yesRevista Colombiana de Medicina Física y Rehabilitación, 2014
La fibromialgia (FM) es un síndrome de dolor musculoesquelético, idiopático, crónico, de baja prevalencia en la población general, que afecta más a mujeres que a hombres en una relación 9:1; sin embargo, su incidencia en el género masculino va en ...
Mauricio Hernández Forero   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Estudio social en hombres que tienen sexo con hombres (HSH): Relevamiento 2007

open access: yes, 2008
En el presente trabajo se exponen los resultados del Estudio Social en Hombres que tienen sexo con hombres, realizado con el apoyo del Fondo Mundial de Lucha contra el Sida, la Tuberculosis y la Malaria, a través del Proyecto “Actividades de apoyo para ...
Barrón López, Sara   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Características de comportamiento sexual en hombres de la Ciudad de México

open access: yesSalud Pública de México, 1999
Objetivo. Determinar las principales características de comportamiento sexual en hombres de la Ciudad de México, incluyendo número de parejas sexuales, antecedentes de enfermedades de transmisión sexual (ETS) y creencias acerca del síndrome de ...
Hernández-Girón Carlos   +4 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

travesía del perineo masculino

open access: yesCirugía del Uruguay, 2020
Presentado en sesión de 26 de julio de ...
Abel Chifflet
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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