Results 31 to 40 of about 2,971,217 (317)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Locating home where discourses of gender and empire intersect: An analysis of selected excerpts from Lady Anne Barnard’s Cape diaries and journals

open access: yesContree, 2015
Lady Anne Barnard’s abundant textual legacy has received a great deal of academic attention with scholars scrutinising her letters, journals and diaries.
Jessica Murray
doaj   +1 more source

Study of care home residents’ and relatives’ expectations and experiences [PDF]

open access: yes, 2011
Care home residents who took part in a study by the Personal Social Services Research Unit (PSSRU) at the University of Kent believe their experience of living in a care home has been better than they expected when they first moved in.
Darton, Robin
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Challenging Hidden Oppression: Mothers Caring for Children with Disabilities

open access: yesCritical Social Work, 2018
There is growing recognition that people with disabilities face oppression in a society which marginalizes those who are different; however, there is evidence that families living with disability also face exclusion, inadequate services and stigmatizing ...
Alice Home
doaj  

Moran’s I Index and KKN-Based LISA

open access: yesJurnal Bina Praja
Stunting in toddlers is a significant nutritional issue that may negatively impact the quality of Indonesia’s future human resources. This study aims to analyze the spatial patterns of stunting prevalence in toddlers in Indonesia as a basis for ...
Yusharto Huntoyungo   +4 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Interpretation of toxicological research data in establishing the no observed adverse effect level (NOAEL) for medicinal products

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Toxicological studies of new pharmaceuticals in laboratory animals represent an obligatory stage in drug risk assessment, designed to identify toxic effects, their potential reversibility, and dependence on dose and/or systemic exposure ...
K. L. Kryshen   +14 more
doaj   +1 more source

Homes for Canadians (II)

open access: yesAmerican, British and Canadian Studies Journal, 2021
According to Giorgio Agamben, the Greek term for ‘habitual dwelling place,’ or ‘habit,’ is ethos. The rise to prominence in the twentieth century of the modern idea of the suburb, or ‘suburbia,’ held open the door to the potential realization of the ...
HOWARD DAVID BRIAN
doaj   +1 more source

Home - About - Disclaimer - Privacy