Results 61 to 70 of about 3,909,302 (311)
BMC Geriatrics, 2018 Background Advance Care Planning (ACP) is the repeated communication and decision-making process between the patient, family, and healthcare professionals.
Irene Aasmul +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Health Economics Review, 2021 Background Nearly 19 million people across OECD countries are living with dementia, and millions of family caregivers are affected by the disease. The costs of informal care are estimated to represent 40–75% of the total dementia cost exceeding formal ...
Renira C. Angeles +6 more
doaj +1 more source
Clinical Medicine, 2010 Care homes are changing, with improved standards and expanding roles, and it is vital that their residents are not excluded or discriminated against by health and social services. Staff are keen to be educated, and investment of time and money is rewarded with improved outcomes in many areas.
openaire +2 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Case Reports in PulmonologyA 63-year-old male with overlap syndrome had high-flow nasal cannula (HFNC) therapy added to his treatment in May 2023 after reporting reduced exercise tolerance due to dyspnea and recurrence of chronic bronchial congestion on existing therapy ...
Jean-Michel Arnal +2 more
doaj +1 more source
Setting priorities to inform assessment of care homes’ readiness to participate in healthcare innovation: a systematic mapping review and consensus process [PDF]
, 2020 © 2020 The Author(s). This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedOrganisational ...
Bunn, F. +8 more
core +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Archives of Gerontology and Geriatrics PlusObjective: This study investigated the relationship between weight loss (WL), decreased food intake (DFI), and mortality among nursing home residents in their 80s and those aged ≥90 years.
Yuri Takada, Kasumi Ikuta, Sakiko Fukui
doaj +1 more source
Evaluation Report: NH Multi-Stakeholder Medical Home Pilot [PDF]
, 2013 The New Hampshire Multi-Stakeholder Medical Home Pilot was initiated in 2008 by the New Hampshire Citizens Health Initiative as a collaborative effort of its Medical Home workgroup, the Center for Medical Home Improvement and the four private New ...
Flieger, Signe Peterson +1 more
core +2 more sources