Results 41 to 50 of about 939,462 (303)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Disparate home range dynamics reflect nutritional inadequacies on summer range for a large herbivore
EcosphereThe spatial distribution of animals has consequences for nutrition, predator–prey dynamics, spread of diseases, and population dynamics in general. Animals must establish a home range to secure adequate resources to fuel their energy needs.
Brittany L. Wagler +7 more
doaj +1 more source
Impacts of shared home range on human-wildlife conflicts
Frontiers in Conservation ScienceHuman-wildlife conflicts (HWCs) are becoming increasingly common in landscapes altered by human activity, often threatening both livelihoods and wildlife conservation. We investigated HWCs in two communities: Bbaale village near Nabugabo Research Site in
Pooja Upadhayay +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Conservation Science and Practice, 2022 Domestic cats (Felis catus) that roam outdoors have increased exposure to hazards to their health and welfare. Outdoor cats can themselves present a hazard to biodiversity conservation and wild animal welfare. Approaches to reducing predation of wildlife
Martina Cecchetti +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Space Use by Brown Bears (Ursus arctos) in the Sikhote-Alin [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2019 Proper management of brown bear populations (Ursus arctos) requires knowledge of their ecology, including space use. Brown bear spatial patterns are particularly poorly understood in the Russian Far East, due to lack of telemetry studies. The aim of this
Ivan V. Seryodkin +3 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Home on the Range: Factors Explaining Partial Migration of African Buffalo in a Tropical Environment
, 2012 Partial migration (when only some individuals in a population undertake seasonal migrations) is common in many species and geographical contexts. Despite the development of modern statistical methods for analyzing partial migration, there have been no ...
Du Preez, Pierre +19 more
core +1 more source
accs-uaa/species-range: Species Range
, 2023 This is the initial release of the species range tool. This tool is written in Python 3 for use in ArcGIS Pro to generate a generalized range map for a species or other taxon from occurrence point data.
Timm Nawrocki
core +1 more source