Results 51 to 60 of about 917,408 (217)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Seasonal variation in the ranging behavior of elephants in the Laikipia‐Samburu ecosystem

Ecology and Evolution
African savanna elephants are a highly mobile species that ranges widely across the diversity of ecosystems they inhabit. In xeric environments, elephant movement patterns are largely dictated by the availability of water and suitable forage resources ...
Loise W. Kuria, Duncan M. Kimuyu, Mwangi J. Kinyanjui, George Wittemyer, Festus W. Ihwagi   +4 more
doaj   +1 more source

Does availability of resources influence grazing strategies in female Svalbard reindeer?

Rangifer, 2003
Foraging strategies and range use in wild female Svalbard reindeer (Rangifer tarandus platyrhynchus) were studied in two areas where the historical grazing pressure differed.
Snorre Henriksen, Ronny Aanes, Bernt-Erik Sæther, Thor Harald Ringsby, Jarle Tufto   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Injury scores and spatial responses of wolves following capture: Cable restraints versus foothold traps

Wildlife Society Bulletin, 2019
Wolves (Canis lupus) have been captured with foothold traps for several decades to equip them with radiocollars for population monitoring. However, trapping in most areas is limited to spring, summer, and autumn as cold winter temperatures can lead to ...
Eric M. Gese, Patricia A. Terletzky, John D. Erb, Kevin C. Fuller, Jeffery P. Grabarkewitz, John P. Hart, Carolin Humpal, Barry A. Sampson, Julie K. Young   +8 more
doaj   +1 more source

Movements of boreal caribou in the James Bay lowlands

Rangifer, 2011
Little is known about the movements and home range of boreal woodland caribou (Rangifer tarandus) in the James Bay lowlands, northern Ontario. Our preliminary study involves the use of GPS collars with Argos satellite system uplink to monitor movements ...
Megan E. Hazell, Mark E. Taylor
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Selection on fish personality differs between a no‐take marine reserve and fished areas

Evolutionary Applications, 2021
Marine reserves can protect fish populations by increasing abundance and body size, but less is known about the effect of protection on fish behaviour. We looked for individual consistency in movement behaviours of sea trout in the marine habitat using ...
Susanna Huneide Thorbjørnsen, Even Moland, David Villegas‐Ríos, Katinka Bleeker, Halvor Knutsen, Esben Moland Olsen   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Big and Fast: GPS Loggers Reveal Long-Range Movements in a Large, Riverine Turtle

Conservation
Rio Grande Cooters (Pseudemys gorzugi) occupy the Rio Grande watershed and have among the smallest ranges of all North American freshwater turtles. Anthropogenic dewatering is considered to have caused range contractions and population declines.
Shashwat Sirsi, Andrew R. MacLaren, Daniel H. Foley, Austin M. A. Bohannon, Jonathan P. Rose, Brian J. Halstead, Michael R. J. Forstner   +6 more
doaj   +1 more source