Results 41 to 50 of about 9,459,907 (254)

The drug treatment outcomes research study (DTORS): Baseline Report

, 2007
This first report from the latest national drug treatment outcomes study describes a baseline population of 1,796 individuals with analyses centred on drug use, offending, treatment contact, social functioning, risk taking and ...
Jones, A; id_orcid, Weston, Samantha, Anderson, T, Donmall, Michael; id_orcid, Moody, A, Millar, T, Dollin, L   +6 more
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

A trial of intermittent preventive treatment and home-based management of malaria in a rural area of The Gambia. [PDF]

, 2011
BACKGROUND: Individual malaria interventions provide only partial protection in most epidemiological situations. Thus, there is a need to investigate whether combining interventions provides added benefit in reducing mortality and morbidity from malaria.
Touray, Ensa, Webb, Emily L, Milligan Paul, Greenwood, Brian M, Milligan, Paul, Emily L Webb, Sowe, Maimuna, Touray Ensa, Ensa Touray, Sesay Sanie, Bojang Kalifa A, Sowe Maimuna, Brian M Greenwood, Sesay, Sanie, Bojang, Kalifa A, Paul Milligan, Kalifa A Bojang, Maimuna Sowe, Sanie Sesay, Greenwood Brian M, Webb Emily L   +20 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Development and Preliminary Validation of the Scale for Evaluation of Psychiatric Integrative and Continuous Care—Patient’s Version

Frontiers in Psychiatry, 2017
This pilot study aimed to evaluate and examine an instrument that integrates relevant aspects of cross-sectoral (in- and outpatients) mental health care, is simply to use and shows satisfactory psychometric properties.
Yuriy Ignatyev, Jürgen Timm, Martin Heinze, Sonja Indefrey, Sebastian von Peter   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Antibiotic Use in Home Treatment of Childhood Diarrhoea in Uyo, Nigeria

Nigerian Journal of Paediatrics
Background: Diarrhoea is a common reason for hospitalisation among under-fives. Caregivers often administer medications, including antibiotics before hospitalisation.
Udoh Ekong, Lovina Ekpo, Frances Okpokowuruk, Kelechi Uhegbu, Ebunlomo Igri   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Home versus outpatient administration of intravenous steroids for multiple-sclerosis relapses: a randomised controlled trial.

, 2006
BACKGROUND: Intravenous steroids are routinely used to treat disabling relapses in multiple sclerosis, and can be administered in an outpatient or home setting. We developed a rating scale that allowed us to compare the two strategies formally in a trial
Riazi, Afsane, Hobart, Jeremy, Heaney, Dominic, Porter, Bernadette, Watt, Hilary, Chataway, Jeremy, Thompson, Alan   +6 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source