Results 51 to 60 of about 9,459,907 (254)

International differences in home treatment for mental health problems. Results of a systematic review.

open access: yes, 2002
BACKGROUND: It is perceived that North American home treatment studies reveal greater success in reducing days in hospital than do European studies. There are difficulties in extrapolating findings internationally.
Henderson, J   +11 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Kansas Soldiers' Home and Mother Bickerdyke Annex, Fort Dodge, Biennial Report Annual Report of the Board of Managers of the Kansas Soldiers' Home and Mother Bickerdyek Home Annual Report of the Board of Managers of the Stater Soldiers Home and Mother Bickerdyke Home

open access: yes, 1889
Gathering title assigned by cataloger. See table of contents for report titles. Most reports scanned from photocopies of the originals and therefore are of poorer quality. Report for fiscal year ending June 30, 1941 issued in two parts.
Kansas Soldiers' Home.
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Physiotherapy Program for Recovery of the Ankle/Foot Complex after Surgery to Correct a Cartilage Defect (Osteochondritis Dissecans) for Implementation in the Period of Home Recovery

open access: yesActa Medica Bulgarica, 2017
The aim of this study is to build a suitable physiotherapy program for recovery of patients undergoing surgery in combination with platelet-rich plasma (PRP) therapy of the ankle joint, intended for implementation in the period of home treatment.
Vassileva-Decheva D., Sokolov Cv.
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Choice of treatment for fever at household level in Malawi: examining spatial patterns. [PDF]

open access: yes, 2007
BACKGROUND: Although malaria imposes an enormous burden on Malawi, it remains a controllable disease. The key strategies for control are based on early diagnosis and prompt treatment with effective antimalarials.
Lawrence N Kazembe   +8 more
core   +1 more source

Home economics, the COVID-19 global pandemic, and beyond

open access: yes, 2021
As the world continues to pivot in response to the disruptive influences of the COVID-19 pandemic, our everyday lives are suspended in a liminal space-no longer completely familiar and lacking predictability; but not yet reconstituted to the new normal ...
Pendergast, Donna, Deagon, Jay
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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