Results 11 to 20 of about 665 (135)

Drug‐resistant epilepsy: Drug target hypothesis and beyond the receptors

open access: yesEpilepsia Open, Volume 7, Issue S1, Page S23-S33, August 2022., 2022
Abstract Epilepsy is a chronic neurological disorder that affects more than 50 million people worldwide. Despite a recent introduction of antiseizure drugs for the treatment of epileptic seizures, one‐third of these patients suffer from drug‐resistant epilepsy (DRE). The therapeutic target hypothesis is a cited theory to explain DRE.
Daniel Fonseca‐Barriendos   +5 more
wiley   +1 more source

Severe Quantitative Scale of Acanthosis Nigricans in Neck is Associated with Abdominal Obesity, HOMA‐IR, and Hyperlipidemia in Obese Children from Mexico City: A Cross‐Sectional Study

open access: yesDermatology Research and Practice, Volume 2022, Issue 1, 2022., 2022
Background. Acanthosis nigricans (AN) is a clinical sign that commonly occurs in obesity; however, its specificity and sensitivity have been controversial. It is unknown if AN severity degree can be a useful marker for cardiometabolic disorders screening.
Ana I. Burguete-García   +13 more
wiley   +1 more source

Protein Phosphatase PP2C Identification in Entamoeba spp

open access: yesBioMed Research International, Volume 2021, Issue 1, 2021., 2021
Entamoeba histolytica is the causative agent of amoebiasis, and Entamoeba dispar is its noninvasive morphological twin. Entamoeba invadens is a reptilian parasite. In the present study, Western blot, phosphatase activity, immunofluorescence, and bioinformatic analyses were used to identify PP2C phosphatases of E. histolytica, E. dispar, and E. invadens.
Abril Navarrete-Mena   +10 more
wiley   +1 more source

Cost-of-illness analysis of chronic urticaria clinical management in five countries of Latin America. [PDF]

open access: yesClin Transl Allergy
Abstract Introduction Chronic spontaneous urticaria (CSU) is a disease with a high impact on the quality of life of patients. There are some evaluations of the economic cost of the disease in developed countries, but there is little information about the economic cost of the disease in developing countries. Our aim was to assess the economic diagnostic
Sánchez J   +8 more
europepmc   +2 more sources

Intranigral Administration of β‐Sitosterol‐β‐D‐Glucoside Elicits Neurotoxic A1 Astrocyte Reactivity and Chronic Neuroinflammation in the Rat Substantia Nigra

open access: yesJournal of Immunology Research, Volume 2020, Issue 1, 2020., 2020
Chronic consumption of β‐sitosterol‐β‐D‐glucoside (BSSG), a neurotoxin contained in cycad seeds, leads to Parkinson’s disease in humans and rodents. Here, we explored whether a single intranigral administration of BSSG triggers neuroinflammation and neurotoxic A1 reactive astrocytes besides dopaminergic neurodegeneration.
Claudia Luna-Herrera   +20 more
wiley   +1 more source

siRNA Design to Silence the 3 ′UTR Region of Zika Virus

open access: yesBioMed Research International, Volume 2020, Issue 1, 2020., 2020
The disease caused by the Zika virus (ZIKV) has positioned itself as one of the main public health problems in Mexico. One of the main reasons is it causes microcephaly and other birth defects. The transmission of ZIKV is through Aedes aegypti and Ae. albopictus mosquitoes, which are found in a larger space of the national territory.
María Perez-Mendez   +4 more
wiley   +1 more source

Factores asociados a la percepción de la validez científica de la homeopatía en un grupo de médicos generales de Perú

open access: yesRevista de la Facultad de Medicina, 2020
Introducción. La homeopatía es una terapia ampliamente utilizada en diversas partes del mundo; sin embargo, su eficacia no se ha comprobado científicamente. Objetivo.
Alvaro Taype-Rondan   +3 more
doaj   +1 more source

A UTILIZAÇÃO DA HOMEOPATIA ASSOCIADA A OUTRAS TERAPIAS PARA O TRATAMENTO DE DOENÇAS CRÔNICAS

open access: yesCogitare Enfermagem, 2009
A homeopatia é comumente utilizada concomitantemente a outras terapias. O objetivo deste estudo foi identificar as terapias utilizadas em associação à homeopatia, e conhecer a credibilidade do usuário nesse tratamento. Estudo de abordagem qualitativa com
Jaqueline Rodrigues Santos   +3 more
doaj   +1 more source

Uso de medicamentos homeopáticos para o tratamento da mastite bovina: Revisão

open access: yesPubvet, 2018
A mastite se apresenta como a doença de maior importância em vacas de leite, devido aos prejuízos causados pela perda de produtividade e descarte de leite de acordo com alguns tratamentos, como os antimicrobianos.
Renan Almeida de Jesus   +1 more
doaj   +1 more source

Avaliação da eficácia de medicamento homeopático BioBoi® na incidência e prevalência de mastite subclínica em vacas leiteiras

open access: yesPubvet, 2023
A mastite é uma das doenças mais frequentes em rebanhos leiteiros causando prejuízos na saúde, produtividade e no bem-estar dos animais e, consequentemente, na rentabilidade das propriedades leiteiras.
Ana Júlia Almeida   +3 more
doaj   +1 more source

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