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Bexarotene signaling in human B and T lymphocytes induces gut-homing receptor expression [PDF]

open access: goldFrontiers in Immunology
BackgroundRetinoic acid (RA) receptors (RARs) in human lymphocytes modulate the humoral and intestinal immune response by regulating target genes, including CD38, TGM2, and gut-homing markers.
Sina Kaiser   +6 more
doaj   +4 more sources

Intranasally applied human olfactory mucosa neural progenitor cells migrate to damaged brain regions

open access: yesFuture Science OA, 2022
Aim: To determine if intranasally administered olfactory mucosa progenitor cells (OMPCs) migrate to damaged areas of brain. Materials & methods: Rowett Nude (RNU) adult rats were injured using the Marmarou model then 2 weeks later received intranasally ...
John M Kronner   +5 more
doaj   +1 more source

Nanoparticles and Mesenchymal Stem Cell (MSC) Therapy for Cancer Treatment: Focus on Nanocarriers and a si-RNA CXCR4 Chemokine Blocker as Strategies for Tumor Eradication In Vitro and In Vivo

open access: yesMicromachines, 2023
Mesenchymal stem cells (MSCs) have a high tropism for the hypoxic microenvironment of tumors. The combination of nanoparticles in MSCs decreases tumor growth in vitro as well as in rodent models of cancers in vivo.
José Joaquín Merino   +1 more
doaj   +1 more source

A place migrants would call home: open-ended constructions and social determinants over time among Ecuadorians in three European cities

open access: yesComparative Migration Studies, 2021
Is there a place in particular that international migrants would call home? How do they talk about it, where does it lie, and what characteristics is it expected to have, given their demographics and patterns of settlement?
Paolo Boccagni   +2 more
doaj   +1 more source

Impaired Dendritic Cell Homing in COVID-19

open access: yesFrontiers in Medicine, 2021
The high mortality of COVID-19 is mostly attributed to acute respiratory distress syndrome (ARDS), whose histopathological correlate is diffuse alveolar damage (DAD).
Lukas Borcherding   +10 more
doaj   +1 more source

Short-range homing in camels: displacement experiments

open access: yesBiology Open, 2021
Camels (Camelus dromedarius) are known to have good navigational abilities and can find their home after displacement to far places; however, there are no studies available on the navigational strategies employed by the camels in homing behavior.
Sofyan H. Alyan
doaj   +1 more source

Homing of radiolabelled xenogeneic equine peripheral blood-derived MSCs towards a joint lesion in a dog

open access: yesFrontiers in Veterinary Science, 2022
Osteoarthritis (OA) is a highly prevalent condition in dogs, causing a substantial reduction in quality of life and welfare of the animals. Current disease management focusses on pain relief but does not stop the progression of the disease.
Charlotte Beerts   +10 more
doaj   +1 more source

Moving to the Outskirts: Interplay Between Regulatory T Cells and Peripheral Tissues

open access: yesFrontiers in Immunology, 2022
Regulatory T cells (Tregs) restrain excessive immune responses and dampen inflammation. In addition to this classical immune suppressive role, Tregs in non-lymphoid tissues also promote tissue homeostasis, regeneration and repair.
Anna Estrada Brull   +2 more
doaj   +1 more source

Organellar Introns in Fungi, Algae, and Plants

open access: yesCells, 2021
Introns are ubiquitous in eukaryotic genomes and have long been considered as ‘junk RNA’ but the huge energy expenditure in their transcription, removal, and degradation indicate that they may have functional significance and can offer evolutionary ...
Jigeesha Mukhopadhyay, Georg Hausner
doaj   +1 more source

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