Results 21 to 30 of about 83,393 (241)

Enhanced Bone Marrow Homing of Natural Killer Cells Following mRNA Transfection With Gain-of-Function Variant CXCR4R334X

Frontiers in Immunology, 2019
Adoptive transfer of natural killer (NK) cells can induce remission in patients with relapsed/refractory leukemia and myeloma. However, to date, clinical efficacy of NK cell immunotherapy has been limited to a sub-fraction of patients.
Emily Levy, Emily Levy, Robert Reger, Filip Segerberg, Melanie Lambert, Caroline Leijonhufvud, Yvonne Baumer, Mattias Carlsten, Mattias Carlsten, Richard Childs   +9 more
doaj   +1 more source

Rescuing Self: Transient Isolation and Autologous Transplantation of Bone Marrow Mitigates Radiation-Induced Hematopoietic Syndrome and Mortality in Mice

Frontiers in Immunology, 2017
The inflamed bone marrow niche shortly after total body irradiation (TBI) is known to contribute to loss of hematopoietic stem cells in terms of their number and function.
Subhajit Ghosh, Subhajit Ghosh, Namita Indracanti, Jayadev Joshi, Jayadev Joshi, Prem Kumar Indraganti   +5 more
doaj   +1 more source

Practicing Home in the Foreign: 'The multiple homing practices of artisan journeymen on the tramp'

Nordic Journal of Migration Research, 2018
Research in migrant practices has recognised that home crystallises into multiple forms subject to constant re-enactment when viewed from the perspective of mobile populations such as nomads and refugees.
Dorte Jagetic Andersen, René Ejbye Pedersen   +1 more
doaj   +1 more source

Avian Conservation and Ecology Home > Vol. 2, Iss. 2 > Art. 1 > Abstract mullie Are Boreal Ovenbirds, Seiurus aurocapilla, More Prone to Move across Inhospitable Landscapes in Alberta’s Boreal Mixedwood Forest than in Southern Québec’s Temperate Deciduous Forest?

Avian Conservation and Ecology, 2007
Population life-history traits such as the propensity to move across inhospitable landscapes should be shaped by exposure to landscape structure over evolutionary time.
Marc Bélisle, André Desrochers, Marc-André Villard   +2 more
doaj   +1 more source

A confinable home-and-rescue gene drive for population modification

eLife, 2021
Homing-based gene drives, engineered using CRISPR/Cas9, have been proposed to spread desirable genes throughout populations. However, invasion of such drives can be hindered by the accumulation of resistant alleles.
Nikolay P Kandul, Junru Liu, Jared B Bennett, John M Marshall, Omar S Akbari   +4 more
doaj   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source

Navigating structure-based drug discovery with emerging innovations in physics- and knowledge-based approaches

npj Drug Discovery
Structure-based drug design is rapidly evolving, driven by advances in both physics-based and knowledge-based methods. These computational approaches are increasingly integrated across all stages of drug discovery. Despite remarkable progress, challenges
Jordy Homing Lam, Vsevolod Katritch
doaj   +1 more source

In vivo Monitoring and Assessment of Exogenous Mesenchymal Stem Cell-Derived Exosomes in Mice with Ischemic Stroke by Molecular Imaging

International Journal of Nanomedicine, 2020
Rong Xu,* Yingying Bai,* Shudan Min, Xiaoxuan Xu, Tianyu Tang, Shenghong Ju Jiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing 210009, People’s ...
Xu R, Bai Y, Min S, Xu X, Tang T, Ju S
doaj  

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Impact of Controller Performance on the Process of Guiding an Armour-Piercing Missile onto a Ground-Based Target [PDF]

Problemy Mechatroniki, 2016
This work presents an analysis of guiding an anti-tank missile (ATGM) onto a ground-based target. The concept presented here is the feasibility of bypassing obstacles in the path of an ATGM when the obstacle coordinates are known prior to firing the ATGM
Łukasz NOCOŃ, Konrad STEFAŃSKI
doaj   +1 more source