Results 61 to 70 of about 3,763,518 (290)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Novel fungicide and neonicotinoid insecticide impair flight behavior in pollen foraging honey bees, Apis mellifera

Scientific Reports
Bees are often exposed to pesticides affecting physiological functions and molecular mechanisms. Studies showed a potential link between altered expression of energy metabolism related transcripts and increased homing flight time of foragers exposed to ...
Anna Keodara, Lukas Jeker, Lars Straub, Daniela Grossar, Jan Müller, Verena Christen   +5 more
doaj   +1 more source

Machine Vision-Based Quantification of Colony-Level Homing Adaptation in Apis mellifera Following Hive Entrance Displacement

Insects
Both hive displacement and entrance relocation can challenge honeybee homing navigation, yet the temporal dynamics of colony-level homing behavior following hive entrance displacement remain poorly quantified.
Run Li, Yuntao Lu, Cunchao Li, Jie Zhang, Wei Wu, Shengping Liu   +5 more
doaj   +1 more source

Targeting of CXCR3 improves anti-myeloma efficacy of adoptively transferred activated natural killer cells

Journal for ImmunoTherapy of Cancer, 2019
Background The peculiar multiple myeloma microenvironment, characterized by up-regulated levels of several inflammatory chemokines, including the CXCR3 receptor ligands CXCL9 and CXCL10, limits NK cell positioning into the bone marrow by interfering with
Valentina Bonanni, Fabrizio Antonangeli, Angela Santoni, Giovanni Bernardini   +3 more
doaj   +1 more source

An unusual homing behavior found in the Sichuan Partridge during the early brooding period

Avian Research, 2020
In this study, we report an unusual homing behavior of the Sichuan Partridge (Arborophila rufipectus) at the Laojunshan National Nature Reserve, Sichuan Province, China.
Yiqiang Fu, Shufang Wang, Benping Chen, Simon Dowell, Zhengwang Zhang   +4 more
doaj   +1 more source

Home Values and Firm Behavior

American Economic Review, 2020
The homes of firm owners are an important source of finance for ongoing businesses. We use UK microdata to show that a £1 increase in the value of the homes of a firm’s directors increases the firm’s investment by £0.03. This effect is concentrated among firms whose directors’ homes are valuable relative to the firm’s assets, that are financially ...
Bahaj, S, Foulis, A, Pinter, G
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Spatiotemporal structure of foraging and path integration errors by fiddler crabs, Leptuca pugilator

Frontiers in Marine Science
Path integration is the navigational process by which animals construct a memory of a previous location by continuously measuring and summing their movements to form a single home vector pointing to the starting location. It is intrinsically error prone,
Ruma Chatterji, John E. Layne
doaj   +1 more source

Avian magnetoreception: elaborate iron mineral containing dendrites in the upper beak seem to be a common feature of birds [PDF]

, 2010
The magnetic field sensors enabling birds to extract orientational information from the Earth’s magnetic field have remained enigmatic. Our previously published results from homing pigeons have made us suggest that the iron containing sensory dendrites ...
Mouritsen, H., Kühbacher, Markus, Kuehbacher, M., Markus Kuehbacher, Fleissner, Gerta, Fleissner, G., Wellenreuther, G., Thalau, Peter, Mouritsen Henrik, Heyers, D., Dominik Heyers, Fleissner Guenther, Wellenreuther, Gerd, Kirsten Schuchardt, Thalau Peter, Mouritsen, Henrik, Thalau, P., Fleissner Gerta, Wellenreuther Gerd, Henrik Mouritsen, Schuchardt Kirsten, Falkenberg Gerald, Gerd Wellenreuther, Schuchardt, Kirsten, Gerald Falkenberg, Guenther Fleissner, Heyers Dominik, Heyers, Dominik, Fleissner, Günther, Falkenberg, G., Schuchardt, K., Peter Thalau, Gerta Fleissner, Falkenberg, Gerald, Kuehbacher Markus   +34 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source