Results 81 to 90 of about 977,991 (352)
CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p. [PDF]
PLoS ONE, 2015 Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour.
Mosavar Farahani +4 more
doaj +1 more source
The intestine: A highly dynamic microenvironment for IgA plasma cells
Frontiers in Immunology, 2023 To achieve longevity, IgA plasma cells require a sophisticated anatomical microenvironment that provides cytokines, cell-cell contacts, and nutrients as well as metabolites.
Katharina Pracht +4 more
doaj +1 more source
A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules. [PDF]
, 1990 The binding of lymphocytes to high endothelial venules (HEV) within peripheral lymph nodes (pln) is thought to be mediated by a lectinlike adhesion molecule termed the pln homing receptor (pln HR). The cloning and sequencing of cDNAs encoding both murine
Fennie, C +5 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Peningkatan Pengetahuan dan Keterampilan STEM@Home bagi Guru-Guru Sains dan Biologi
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat, 2023 STEM (Science, Technology, Education, and Mathematics) adalah salah satu pendekatan pembelajaran sains terintegrasi yang bermanfaat untuk melatihkan problem solving skills dan keterampilan abad 21, serta menjadi salah satu model pembelajaran inovatif yang disarankan untuk diterapkan di kelas sains.
Murni Ramli +8 more
openaire +1 more source
Organ-specific features of natural killer cells. [PDF]
, 2011 Natural killer (NK) cells can be swiftly mobilized by danger signals and are among the earliest arrivals at target organs of disease. However, the role of NK cells in mounting inflammatory responses is often complex and sometimes paradoxical.
La Cava, Antonio +3 more
core +1 more source
Methods in molecular biology, 2019 Over the past two decades, several coronavirus (CoV) infectious clones have been engineered, allowing for the manipulation of their large viral genomes (~30 kb) using unique reverse genetic systems.
Anthony R. Fehr
semanticscholar +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
CD112 Regulates Angiogenesis and T Cell Entry into the Spleen
Cells, 2021 Junctional adhesion proteins play important roles in controlling angiogenesis, vascular permeability and leukocyte trafficking. CD112 (nectin-2) belongs to the immunoglobulin superfamily and was shown to engage in homophilic and heterophilic interactions
Erica Russo +9 more
doaj +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
, 2018 For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
core +1 more source