Results 191 to 200 of about 1,477,310 (345)
En este artículo, me propongo mostrar cómo el acto de cuidar está esencialmente atravesado por significados biológicos, psicológicos, sociales y morales. Esto lo convierte en un núcleo teórico sobre el cual es posible desarrollar un enfoque moderadamente naturalista, pero filosóficamente relevante y significativo.
openaire +1 more source
Homo Roboticus: Creating Synergies Among Humans, Technology, Science, and Art [Book review] [PDF]
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Modeling and experimental analyses for Chitosan/Zinc oxide nanocomposite. [PDF]
Elhaes H +3 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Genetic and epidemiological patterns of primary immunodeficiency diseases in Eastern Iranian patients. [PDF]
Salehi M +6 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Symmetrical D-π-A-π-D indanone dyes: a new design for nonlinear optics and cyanide detection. [PDF]
Keleş E +4 more
europepmc +1 more source

