Results 211 to 220 of about 774,972 (362)

Synthesis and pyroelectric response of disperse red 1 functionalized silicones: cyclic monomer, homopolymer, and block copolymer derivatives.

Mater Horiz
Beccard MS, Raman Venkatesan T, Taddei F, Baraldi L, Mezzenga R, Nüesch FA, Opris DM.   +6 more
europepmc   +1 more source

Table-top three-dimensional photoemission orbital tomography with a femtosecond extreme ultraviolet light source. [PDF]

Nat Commun
Bennecke W, Dinh TL, Bange JP, Schmitt D, Merboldt M, Weinhagen L, van Wingerden B, Frassetto F, Poletto L, Reutzel M, Steil D, Luke DR, Mathias S, Jansen GSM.   +13 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

First principles electronic transport study of triacetone triperoxide adsorbed on Ti₃C₂O₂ and Ti₃C₂F₂ MXene monolayers. [PDF]

Discov Nano
Tomović AŽ, Djurišić I, Dražić MS, Jovanović VP, Zikic R.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Al- and Ga-doped graphitic carbon nitride as a temozolomide nanocarrier platform: a DFT study of adsorption and interfacial interactions. [PDF]

Nanoscale Adv
Yousuf M, Musa MS, Bhuiyan AM, Uzzaman M, Hossain MM, Dey K.   +5 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Molecular insights into the effect of small molecule impurities in the ring-opening polymerization of [PCl₂N]₃ using quantum mechanical analysis.

Phys Chem Chem Phys
Xue Y, Salmon CR, Gogonea V.
europepmc   +1 more source

Atom-in-Molecule Analysis, Density Function Theory Research, Spectroscopy, Charge Transfer, and (Static, Dynamic) Nonlinear Optical Effects of (Z)4,4^'-Bis[-3-N-Ethyl-2-N'-(Phenylimino) Thiazolidin-4-One] Methane. [PDF]

ChemistryOpen
Benyahlou ZD, Triki Baara F, Yahiaoui S, Saidj M, Dermeche K, Harir M, Megrouss Y, Djafri A, Chouaih A, Bendif H, Elfalleh W, Taha TH, Chaudhary AA, Garzoli S.   +13 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source