Results 61 to 70 of about 120,385 (244)

Downsizing Electrophilic MAX‐Derived Helical Zipper Peptides to Covalently Bind and Degrade Oncogenic MYC

open access: yesAngewandte Chemie, EarlyView.
Oncogenic MYC is a transcription factor that is difficult to inhibit. However, precise positioning of an acrylamide electrophile in MAX to covalently bond to the unique Cys438 in MYC, enabled shortening and optimizing of MAX‐derived, helix‐constrained peptides with high‐affinity and selectivity.
Aline Dantas de Araujo   +7 more
wiley   +2 more sources

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li   +9 more
wiley   +1 more source

Uma nova economia (ou a vida como jogo)

open access: yesAnuário de Literatura, 2008
Este ensaio pretende uma leitura da vida como jogo proposta por Georges Bataille em face aos romances marginais contemporâneos Cidade de Deus de Paulo Lins e Capão Pecado de Ferréz.
Flavia Leticia Biff Cera
doaj   +1 more source

Non‐Coding Transcripts From Diversified Members of IgLec Family Protect Antiviral Effectors From Viral miRNA

open access: yesAdvanced Science, EarlyView.
The IgLec gene family generates both protein‐coding antiviral effectors and non‐coding transcripts. Upon viral infection, non‐coding transcripts are preferentially targeted by viral miR‐N48, thereby buffering protein‐coding isoforms from repression. Depletion of these decoy transcripts compromises antiviral defense, revealing a non‐coding RNA‐mediated ...
Ying Huang   +5 more
wiley   +1 more source

Between the Pure and the Impure: The Peculiar Case of the homo sacer

open access: yes, 2020
According to Durkheim, the notion of ‘sacred’ is per se ambivalent, because it includes antinomic notions such as the pure and the impure. This theory would be justified by the original ambiguity of the Latin sacer.
Corre, Nicolas, Nicolas Corre
core   +1 more source

Coordination Chemistry of Single‐Atom Catalysts in Expediating Kinetics for Advanced Lithium‐Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
This review elucidates the catalytic mechanisms of single‐atom catalysts (SACs) in accelerating lithium polysulfides redox kinetics. Subsequently, the modifications brought by asymmetric coordination chemistry and dual‐atom coordination structures in terms of geometric configuration engineering, molecular orbital hybridization, and interfacial charge ...
Peng Chen   +7 more
wiley   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Homo Sacer, de Giorgio Agamben

open access: yesRevista da Faculdade de Direito da Universidade de Uberlândia, 2017
Resenha de ...
Juliane Caravieri Martins
doaj  

Deviance or Homo sacer? Foucault, Agamben and Foetal Diagnostics

open access: yesScandinavian Journal of Disability Research, 2006
This article compares the perspectives of Foucault and Agamben on biopolitics. The dichotomy normality/deviance is central to Foucault's analyses of modern subjectivities, while the Sovereign/Homo sacer dichotomy has a similar position according to ...
Thorvald Sirnes
doaj   +1 more source

THE HOMO SACER PARADOX: BETWEEN THE ABANDONMENT AND THE BAND

open access: yes, 2013
In this paper, I analysis the way in which the contemporary Homo sacer presents us itself in face a dual structure: the abandonment and band. This hybrid concept has your heart in the inclusion of some individuals in some State, and presents in face of a
Amitrano, Georgia
core   +1 more source

Home - About - Disclaimer - Privacy