Results 161 to 170 of about 214,984 (288)

Regulatory Effects of Ammonium Chloride in an In Vitro Model of Hepatic Encephalopathy: Mechanisms Involving ACTA2‐Mediated Cytoskeletal Remodeling

open access: yesiLABMED, EarlyView.
Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang   +6 more
wiley   +1 more source

Homo sapiens could have hunted with bow and arrow from the onset of the early Upper Palaeolithic in Eurasia. [PDF]

open access: yesiScience
Kitagawa K   +7 more
europepmc   +1 more source

Structural Exploration on Palmitoyltransferase DHHC3 from Homo sapiens. [PDF]

open access: yesPolymers (Basel), 2022
Tang M   +5 more
europepmc   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Fossil ribcages of Homo sapiens provide new insights into modern human evolution. [PDF]

open access: yesCommun Biol
López-Rey JM   +7 more
europepmc   +1 more source

Child dietary patterns in Homo sapiens evolution: A systematic review. [PDF]

open access: yesEvol Med Public Health, 2022
Iannotti LL   +8 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Editor’s Essay: Good-bye Homo Sapiens

open access: yesIAFOR Journal of Arts & Humanities, 2018
Alfonso J. García-Osuna
doaj   +1 more source

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