ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött +17 more
wiley +1 more source
Early hominins from Morocco basal to the Homo sapiens lineage. [PDF]
Hublin JJ +28 more
europepmc +1 more source
Early presence of Homo sapiens in Southeast Asia by 86-68 kyr at Tam Pà Ling, Northern Laos. [PDF]
Freidline SE +30 more
europepmc +1 more source
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer +2 more
wiley +1 more source
Mapping the inter- and intra-genic codon-usage landscape in <i>Homo sapiens</i>. [PDF]
Arshad M +5 more
europepmc +1 more source
Changes in plasticity of the pelvic girdle from infancy to late adulthood in Homo sapiens. [PDF]
Kubicka AM.
europepmc +1 more source
Escuela abierta y mundos posibles : áreas del conocimiento en los nuevos contextos
Resumen basado en el de la publicaciónEn el contexto de crisis económica, social y cultural, irrumpen nuevas pautas y principios de la posmodernidad, y se abren nuevos espacios con las tecnologías comunicacionales. Estas dimensiones atraviesan la escuela,
Berdichevsky, Patricia +4 more
core
MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai +8 more
wiley +1 more source
The Gene Encoding the RCC1 (Regulator of Chromosome Condensation 1) Protein in Drosophila melanogaster and Homo sapiens. [PDF]
Turtapkina VA +10 more
europepmc +1 more source
HGCA2.0: An RNA-Seq Based Webtool for Gene Coexpression Analysis in Homo sapiens. [PDF]
Zogopoulos VL +13 more
europepmc +1 more source

