Results 31 to 40 of about 214,984 (288)

Genetic analysis of lice supports direct contact between modern and archaic humans.

open access: yesPLoS Biology, 2004
Parasites can be used as unique markers to investigate host evolutionary history, independent of host data. Here we show that modern human head lice, Pediculus humanus, are composed of two ancient lineages, whose origin predates modern Homo sapiens by an
David L Reed   +4 more
doaj   +1 more source

Do australopithecus ao homo sapiens sapiens e ao "homo cretinensis"

open access: yes, 2021
UIDB/04647/2020 UIDP/04647/2020O presente texto, sob a forma de ensaio reflete, tendo por base outras reflexões do autor sobre o tema, acerca da relação entre a natureza e a cultura sendo a primeira a base da cultura e a segunda tudo o que a espécie ...
Carvalho, Nuno
core   +1 more source

Massive cranium from Harbin in northeastern China establishes a new Middle Pleistocene human lineage

open access: yesThe Innovation, 2021
It has recently become clear that several human lineages coexisted with Homo sapiens during the late Middle and Late Pleistocene. Here, we report an archaic human fossil that throws new light on debates concerning the diversification of the Homo genus ...
Xijun Ni   +12 more
doaj   +1 more source

Between science, science-fiction and COVID19 as a way to interpret the ontological realm of COVID19. Humanity in the post-COVID19 and re-application of knowledge.

open access: yesAcademicus International Scientific Journal, 2022
The current article is an attempt by the authors to present a bioethical case, or rather a search being undertaken to develop tools to interpret the novel ontological realm which has been created, and continues to be transformed in real time, by the ...
Chidinma Iheanetu, Roman Tandlich
doaj   +1 more source

Dispersal of Homo sapiens around the Indian Ocean rim: a geometric morphometric study of craniofacial diversity. [PDF]

open access: yes, 2007
This thesis explores craniofacial diversity found in Homo sapiens around the Indian Ocean rim. Three dimensional landmark data, taken directly from the craniofacial skeleton, are examined in relation to the hypothesised southern dispersal route taken by ...
Buck, Trudi Jane
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Pirmykštis žmogus:tradicinė ir dabartinė interpretacija

open access: yesProblemos, 2014
Straipsnyje bandoma sugretinti tradicinę ir dabartinę pirmykščio žmogaus interpretaciją, parodoma, kaip ją paveikė paskutinių dviejų dešimtmečių archeologiniai ir paleantropologiniai atradimai.
Edmundas Gendrolis
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Seguendo le orme di Homo sapiens: un viaggio lungo sei milioni di anni [PDF]

open access: yes, 2018
Pikaia ha letto per voi “Il giro del mondo in sei milioni di anni” scritto da Guido Barbujani e Andrea Brunelli (Il Mulino). La tendenza a spostarci accompagna la nostra specie da sei milioni di anni ovvero sin dalla nostra origine siamo migrati verso ...
Mauro Mandrioli
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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