Results 51 to 60 of about 214,984 (288)

Ranking U-Sapiens 2013-1 [PDF]

open access: yes, 2014
Objetivos: (1) Publicar el listado de universidades certificadas por Sapiens Research Group; (2) el séptimo reporte de las mejores instituciones de educación superior colombianas según indicadores de investigación; (3) el listado de las 10 IES que más ...
Sapiens Research Group   +1 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Ranking U-Sapiens 2013-2 [PDF]

open access: yes, 2014
Objetivos: Publicar el listado de universidades certificadas por Sapiens Research Group; el octavo reporte de las mejores instituciones de educación superior colombianas según indicadores de investigación; el listado de las IES que más han subido y ...
Sapiens Research Group
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Del homo economicus al Homo Sapiens

open access: yesThēmis, 2010
En este trabajo, Thaler hace diez predicciones sobre el futuro de la Economía. Futuro en el que, nos dice el autor, se hace cada vez más claro aquello que quizás siempre supimos: los hombres no somos completamente racionales, nuestra especie no es la del
Richard Thaler
doaj  

Homo sapiens: cancer or parasite?

open access: yesEthics in Science and Environmental Politics, 2014
Two contrasting ideas, that humans are ‘part of the ecosystem’ (i.e. a constitutive element of the ecosystems they exploit) and that humans are ‘a cancer on the Earth’, are examined in the light of the current despoliation of the biosphere.
D Pauly
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Homo sapiens — en vetenskaplig kulturkrock

open access: yesKulturella Perspektiv, 2000
The completion of the HUGO-project will in a dramatic way alter basic research in all areas of biology. The use of the new information will be facilitated by emergence of bioinformatic and technical development for studies of all genes, which are ...
Erik Lundgren
doaj   +1 more source

Ranking U-Sapiens 2012-2 [PDF]

open access: yes, 2012
Objetivos: (1) publicar la sexta versión (o reporte) de las mejores universidades colombianas según indicadores de investigación; (2) analizar la dinámica del índice u-sapiens (Ius); (3) mostrar los resultados de las correlaciones de los puntajes de la ...
Sapiens Research Group   +1 more
core  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

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