Results 71 to 80 of about 3,286,968 (371)

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Effect of Torso Non-Homogeneities in the quasi-static inverse problems arising in electrocardiology

open access: yesMoroccan Journal of Pure and Applied Analysis, 2019
In the present paper, an homogeneous and non-homogeneous inverse problem constrained by the stationary problem in electrocardiology representing the heart, lungs surfaces, and torso model is investigated.
Ainseba BedrEddine   +2 more
doaj   +1 more source

A Strategy toward Realizing Ultrashort Channels and Microstructures Array by Piezoelectric Inkjet Printing

open access: yesNanomaterials, 2019
Inkjet printing has been proved to be a powerful tool in the cost-effective ambient deposition of functional materials for the fabrication of electronic devices in the past decades.
Jianqiu Chen   +9 more
doaj   +1 more source

Dynamics Analysis for the Random Homogeneous Biased Assimilation Model

open access: yesMathematics, 2023
This paper studies the evolution of opinions over random social networks subject to individual biases. An agent reviews the opinion of a randomly selected one and then updates its opinion under homogeneous biased assimilation. This study investigates the
Jiangbo Zhang, Yiyi Zhao
doaj   +1 more source

Homogeneous time-invariant systems [PDF]

open access: yes, 1999
It is well known that linear time-invariant (LTI) systems produce exponential outputs in response to exponential inputs. The purpose of this paper is to draw attention to the fact that the same result holds for the broader class of homogeneous time ...
Vaidyanathan, P. P.
core   +1 more source

Homogenization of a non-homogeneous fluid

open access: yes, 2018
We consider a non--homogeneous incompressible and heat conducting fluid confined to a 3D domain perforated by tiny holes. The ratio of the diameter of the holes and their mutual distance is critical, the former being equal to $ ^3$, the latter proportional to $ $, where $ $ is a small parameter.
Feireisl, Eduard   +2 more
openaire   +2 more sources

The homogeneity conjecture [PDF]

open access: yesProceedings of the National Academy of Sciences, 1979
We show that, for any function f in which Kleene's O is computable, the ordering of Turning degrees (i.e., degrees of difficulty of computation of functions) is not isomorphic to the ordering of degrees of functions from which f is computable. This refutes a well-known
openaire   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

An ultrasound-promoted green approach for the synthesis of 3-(indol-3-yl)-3-hydroxyindolin-2-ones catalyzed by Fe(III) [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
Ferric chloride hexahydrate was used as a recyclable homogeneous catalyst in aqueous media for the synthesis of 3-(indol-3-yl)-3-hydroxyindolin-2-ones under sonication.
Tabatabaeian Khalil, Khorshidi Alireza
doaj   +1 more source

Intersection graphs of graded ideals of graded rings

open access: yesAIMS Mathematics, 2021
In this article, we introduce and study the intersection graph of graded ideals of a graded ring. The intersection graph of G−graded ideals of a graded ring R, denoted by GrG(R), is undirected simple graph defined on the set of nontrivial graded left ...
Tariq Alraqad   +2 more
doaj   +1 more source

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