Results 81 to 90 of about 2,700,208 (322)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

$N$-homogeneous superalgebras

Journal of Noncommutative Geometry, 2008
We develop the theory of N -homogeneous algebras in a super-setting, with particular emphasis on the Koszul property. To any Hecke operator \mathcal R on a vector ...
Hai, Phùng Hô, Kriegk, Benoît, Lorenz, Martin   +2 more
openaire   +3 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Improvement of Homogeneous Catalysts for Methanol Carbonylation to Acetic Acid: Effects of Three-Ethyl Phosphine and Three-Phenyl Phosphine as Ligands [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The carbonylation of methanol is a catalytic homogeneous process that has been expanded for industrial applications. The metal-organic complexes utilized as homogeneous catalysts for acetic acid production encompass Co, Ru, Ir, Ni, and Rh-based catalysts.
Mohammad Shareei, Reza Mosayebi Behbahani, Asadollah Farhadi, Fatemeh Rashedi   +3 more
doaj   +1 more source

Forest-skein groups II: construction from homogeneously presented monoids [PDF]

, 2022
Arnaud Brothier
openalex   +1 more source

>k-homogeneous infinite graphs

, 2017
In this article we give an explicit classification for the countably infinite graphs $\mathcal{G}$ which are, for some $k$, $\geq$$ k$-homogeneous. It turns out that a $\geq$$k-$homogeneous graph $\mathcal{M}$ is non-homogeneous if and only if it is ...
Ahlman, Ove
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Totally homogeneous networks

National Science Review, 2019
Abstract In network science, the non-homogeneity of node degrees has been a concerning issue for study. Yet, with today's modern web technologies, the traditional social communication topologies have evolved from node-central structures into online cycle-based communities, urgently requiring new network theories and tools.
Dinghua Shi, Linyuan Lü, Guanrong Chen
openaire   +3 more sources

Mechanical Homogenization Increases Bacterial Homogeneity in Sputum [PDF]

Journal of Clinical Microbiology, 2014
ABSTRACT Sputum obtained from patients with cystic fibrosis (CF) is highly viscous and often heterogeneous in bacterial distribution. Adding dithiothreitol (DTT) is the standard method for liquefaction prior to processing sputum for molecular detection assays.
Joshua R, Stokell, Ammad, Khan, Todd R, Steck   +2 more
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source