Results 211 to 220 of about 7,193,350 (237)

When Two Dimensions Matter: A Critical Review of Recent Comprehensive Two‐Dimensional Gas Chromatography Applications in Food Analysis

open access: yesChemFoodChem, EarlyView.
Comprehensive two‐dimensional gas chromatography (GC×GC) is gaining importance in food analysis, particularly for volatile and aroma‐related compounds. This review examines recent applications across plant‐, animal‐, and other food matrices, revealing trends in sample preparation, column selection, modulation and detection, while highlighting ...
Ana Jano   +3 more
wiley   +1 more source

Large parameter asymptotic analysis for homogeneous normalized random measures with independent increments

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Homogeneous normalized random measures with independent increments represent a broad class of Bayesian nonparametric priors and thus are widely used. In this article, we obtain the strong law of large numbers, the central limit theorem (CLT), and the functional central limit theorem (fCLT) of such measures when the concentration parameter a ...
Junxi Zhang, Shui Feng, Yaozhong Hu
wiley   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke   +12 more
wiley   +1 more source

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Diqin Yan   +6 more
wiley   +1 more source
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